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Minimum energy ofr2 - PowerPoint PPT Presentation

Short fast history of protein design

Short fast history of protein design. Site-directed mutagenesis -- protein engineering (J. Wells, 1980's) Coiled coils, helix bundles (W. DeGrado, 1980's-90's) Extreme protein stabilization (S. Mayo, 1990's) Binding pocket design (H. Hellinga, 2000) New fold design (B. Kuhlman, 2002-4)

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Minimum energy ofr2 - PowerPoint PPT Presentation

Short fast history of protein design