HLAMatchmaker-Based Analysis of MICA Antibody Reactivity Patterns. Rene J. Duquesnoy 1 , Justin W. Mostecki 2 , Jayasree Hariharan 2 , Kristi Colacioppo 2 , Bryan Ray 2 and Ivan Balazs 2 1 University of Pittsburgh Medical Center and 2 Tepnel Lifecodes Corporation. IntroductionBy bikita
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The Untold Story. ANTIBODIES. Brought to you by the Flying J’s Jenna Houmes, Julia Coffin, Jennifer Rose, and Jenny Stearman. Presentation Outline. Background Information Structure- Shape, T and B cells, macrophages Function- Interaction with antigens Types of antibodies- 5 types
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Antibodies. Antibodies produced by cells of the Immune System recognize foreign antigens and mark them for destruction. .
Antibodies. Secreted by B lymphocytes Great diversity and specificity: >10 9 different antibodies; can distinguish between very similar molecules Tag particles for clearance/destruction Protect against re-infection (vaccines). Antibody Structure.
Antibodies. Ag-Ig Interaction. BCR. IgM. Secreted vs Membrane Bound. IgG. Membrane bound IgD and IgM. FcR. FcR allow antibodies to interact with cells of both the specific and non-specific immune systems.
Antibodies. How does your body fight infections?. Introduction. The body has to be ready to fight off anything which could do damage to it One of the ways that it can do this is by releasing lots of chemicals that will destroy anything in their path
Antibodies. Immunoglobulins—gamma globulin portion of blood Proteins secreted by plasma cells Capable of binding specifically with antigen detected by B cells. Basic Antibody Structure. T-or Y-shaped monomer of four looping linked polypeptide chains
Antibodies. Heroes of the humoral response. Adaptive immunity. Lab #3. 1/25/11. Adaptive defenses. Humoral immunity. Antigen-antibody complex. Antigen. Antibody. Inactivates by. Fixes and activates. Neutralization (masks dangerous parts of bacterial exotoxins; viruses).