Mhc locus - PowerPoint PPT Presentation

The Human Genomes

The Human Genomes. Gil McVean, Department of Statistics, Oxford. Genetic variation among humans. http://www.ncbi.nlm.nih.gov/genome/guide/human/. How do we differ? – Let me count the ways. Single nucleotide polymorphisms 1 every few hundred bp, mutation rate* ≈ 10 -9

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Chapter 15

Chapter 15. DNA-Based Tissue Typing. Objectives. Describe the structure of the MHC locus that encodes the HLA antigens. Explain the role of these antigens in tissue engraftment and rejection. Describe the laboratory methods used to identify HLA antigens by serology testing.

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