Methemoglobinemia - PowerPoint PPT Presentation

Pigments and accumulations

Pigments and accumulations. Decreased ATP production Increased mitochondrial permeability Leakage of Ca++ Ca-activated hydrolases degrade lipid, protein, RNA, DNA Denatured nucleic acid and protein may be large or small After initial “blebbing” of ER or plasma membranes, membranes burst

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IMPLEMENTATION &amp; USE of CRRT in PEDIATRIC INTOXICATIONS

IMPLEMENTATION &amp; USE of CRRT in PEDIATRIC INTOXICATIONS. Patrick D. Brophy MD University of Michigan Pediatric Nephrology. OBJECTIVES. Review pharmacokinetic properties When to implement therapy Review extracorporeal techniques for toxin removal Other factors involved

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450 views • 26 slides