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Liu et al. (1995) The Journal of Biological Chemistry

Role of Mitogen-activated Protein Kinase Phosphatase During the Cellular Response to Gentoxic Stress :Inhibition of c-Jun N-Terminal Kinase Activity and AP-1 Dependent Gene Activation. Liu et al. (1995) The Journal of Biological Chemistry. UV Light. Introduction.

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353 views • 21 slides

Coiled coil domain

Introduction. Coiled coil domain. Stress signal e.g. H2O2. S S. S S. ASK1. ASK1. ASK1. ASK1. ASK1. ASK1. ASK1. ASK1. Poly ubiquitination, Degradation Cullin degradation. PP5. Conformational change. Trx1. Trx1. Trx1. Trx1. Thr845. P. P. Trans-autophosphorylation. Thr845.

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217 views • 10 slides

Coiled coil domain

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191 views • 6 slides

Time (minutes)

2. 1. 0. 0. 10. 20. 30. 3. 2. 1. 0. 0. 10. 20. 30. A. Time (minutes). 0. 10. 20. 30. Phospho ERK1/2. ERK1/2. Phospho-ERK1/2 : ERK1/2 IDV ratio. Phospho-ERK1/2 blot densitometry. B. Time (minutes). 0. 10. 20. 30. Phospho JNK. JNK. Phospho-JNK : JNK IDV ratio.

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159 views • 1 slides

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Jnk - PowerPoint PPT Presentation

Liu et al. (1995) The Journal of Biological Chemistry

Coiled coil domain

Coiled coil domain

Time (minutes)