WELCOME TO THE HEALTHCARE UPDATE FOR OCTOBER 2005. PRESENTING NEWS ABOUT STAFF AND VOLUNTEERS . Grace. All children touch us in different ways but Grace’s struggle with Pneumonia went on for many days and she became extremely exhausted.By tirza
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Tumour Markers. Tumor Biology. Cancer cells behave as independent cells, growing without control to form tumors. Tumors grow in a series of steps.
Tumour Markers. Annual Practice Nurse Conference 2016 Kate Murphy (OLN) & Aoife O’Shea (Research Nurse). Tumour Markers . The concept of tumour markers can mean anything that helps in the diagnosis of cancer In a more restricted sense it refers to the biochemical detection of cancer.
Tumour immunotherapy. Raymond Steptoe Senior Research Fellow Diamantina Institute for Cancer, Immunology and Metabolic Medicine University of Queensland, Princess Alexandra Hospital firstname.lastname@example.org. Overview. History Review of immune effectors & immunity Basis for immunotherapy
Tumour Immunology. Immune surveillance : The immune system surveys the body for malignancies, eliminating tumours or slowing their growth. Cell mediated NK cells MQ :Ag presentation & cytokines (TNF) Tcytotoxic :major effector mechanism γ - δ &mucosacells:skin
Tumour immunology. J. Ochotná. Tumor antigens. Antigens specific for tumors (TSA) complexes of MHC gp I with abnormal fragments of cellular proteins - chemically induced tumors - leukemia with chromosomal translocation
Tumour karyotype. Spectral karyotyping showing chromosomal aberrations in cancer cell lines. Chromosomal aberrations. Segments of DNA that get duplicated Gains Segments of DNA that get deleted Losses
Tumour immunology. Tumor antigens. Tumor – specific antigens (TSA) complexes of MHC gp I with abnormal fragments of cellular proteins (chemically induced tumors, leukemia with chromosomal translocation)
Carotid body tumour. Carotid Aneurysm. ICA ANEURYSM- ANGIOGRAPHIC. Moyamoya disease.
Tumour Suppressor Genes. TSGs code for proteins that inhibit cell division Mutations can cause the proteins to be inactivated and may thus deprive cells of needed restraints on proliferation. Ways of inactivating a TSG. Active growth promoter. S. P53 – protein of 53kDa Rb
27. Tumour immunology - tumour antigens, mechanisms of defence. 28. Alloimmune reaction. Types of transplantations and immunological examination before transplantation. Immunologically privileged tissues.