'Hla antibodies' presentation slideshows

838 views • 71 slides

Objectives

Objectives. Overview of HLA genes and their function Importance of HLA in solid organ transplantation Overview of HLA typing and histocompatibility testing in solid organ transplantation. HLA testing in solid organ transplantation. Dr. Robert Liwski, MD, PhD, FRCPC

1.05k views • 62 slides

PRA = 36% (21/58)

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627 views • 62 slides

Lymphocyte proliferation (stimulation assay)

Lymphocyte proliferation (stimulation assay). Direct cytotoxicity assay. PBMC. Mixed lymphocyte reaction. -Poor reproducibility - Radioactivity. Lymphocyte stimulation assay. Limiting dilution analysis. MLR ? Cytokine production, proliferation or cytotoxicity

5.39k views • 32 slides

The Ubiquitous HLA System: applications in transfusion and transplantation

The Ubiquitous HLA System: applications in transfusion and transplantation. Dr Mary Purna Chacko Department of Transfusion Medicine and Immunohaematology Christian Medical College and Hospital, Vellore ISBTI 2012. Highly polymorphic cell surface molecules

568 views • 19 slides

Transplantation

Transplantation. graft. Donor. Recipient/patient. HLA antibodies. Presence of Donor specific antibody (DSA, HLA antibodies) increases graft rejection. Am J Transplant. (2010) 10:582-9. Flow cytometry crossmatch (FCXM) Testing for HLA Antibodies. Positive: ?MCF >= 50. MCF.

267 views • 5 slides