'Heparan sulfate' presentation slideshows

BIOLOGIE DU DEVELOPPEMENT

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Let the Sun Shine In!!

Let the Sun Shine In!!. Wise Traditions London March 17, 2012 Stephanie Seneff MIT. You can Download My Slides! http:// people.csail.mit.edu/seneff. The only reason to worry about inadequate sun exposure is the possibility of a vitamin D deficiency.

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Glycosaminoglycans

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Selected Genetic Disorders & Primary Immunodeficiency States

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Carbohydrates

Carbohydrates. Carbohydrates (glycans) have the following basic composition:. Monosaccharides - simple sugars with multiple OH groups. Based on number of carbons (3, 4, 5, 6), a monosaccharide is a triose , tetrose , pentose or hexose .

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Wallace McKeehan Center for Cancer & Stem Cell Biology

II. II. F. F. III. III. HSPG. SNT1. Grb2. SHP2. sos. sos. Ras. Grb2. SNT1. AKT. PI3K. Raf. PKC. PLC- g. PLC- g. MEK. ?. ERK1/2. Forty Years of FGF: Regulator of Cellular & Metabolic Homeostasis. Wallace McKeehan Center for Cancer & Stem Cell Biology. The Klothos.

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Sulfated Glycosaminoglycans & Hyaluronan Chapter 11 April 13, 2004 Jeff Esko jesko@ucsd

Sulfated Glycosaminoglycans & Hyaluronan Chapter 11 April 13, 2004 Jeff Esko jesko@ucsd.edu. GLYCOSAMINOGLYCANS (GAGs). CHONDROITIN/DERMATAN SULFATE. HEPARAN SULFATE. P. S. S. S. S. S. Ser-O-. S. S. S. S. -O-Ser. NS. NS. 2S. NS. S. N-LINKED. KERATAN SULFATE. CHAINS. S.

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Wallace McKeehan Center for Cancer & Stem Cell Biology

II. II. F. F. III. III. HSPG. SNT1. Grb2. SHP2. sos. sos. Ras. Grb2. SNT1. AKT. PI3K. Raf. PKC. PLC- g. PLC- g. MEK. ?. ERK1/2. Forty Years of FGF: Regulator of Cellular & Metabolic Homeostasis. Wallace McKeehan Center for Cancer & Stem Cell Biology. The Klothos.

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The Glycosaminoglycans

The Glycosaminoglycans. Heparan sulphate structure. Proteoglycan complex. Collagen Fiber. Proteoglycan molecules form complexes by noncovalently attaching to long polysaccharide molecules. Polysaccharide molecule. Proteoglycan molecule. Collagen fibers are embedded in a web of

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Glycosaminoglycan-Binding Proteins Lecture 25, Chapter 29 May 11, 2004 Jeff Esko

Glycosaminoglycan-Binding Proteins Lecture 25, Chapter 29 May 11, 2004 Jeff Esko. Types of Glycan-Binding Proteins. Glycosyltransferases and modifying enzymes Antibodies induced by carbohydrate antigens Animal Lectins: P,C,S,R,L and I-type (Lectures 19-23)

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Essentials of Glycobiology May 14, 2002 Jeff Esko

Essentials of Glycobiology May 14, 2002 Jeff Esko. Bacterial and viral carbohydrate-binding proteins. Types of Carbohydrate-Binding Proteins. Glycosyltransferases and modifying enzymes Antibodies induced by carbohydrate antigens Plant Lectins: Con A, PHA, WGA, and many others

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Carbohydrates are ubiquitous modifications of eukaryotic cell surface proteins and lipids.

Carbohydrates are ubiquitous modifications of eukaryotic cell surface proteins and lipids. Glycans. Localization of glycoconjugates in intracellular and extracellular compartments . Glycans. Functions. Extrinsic functions resulting from glycan-lectin interactions. Intrinsic functions

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Chap. 7B. Carbohydrates and Glycobiology

Chap. 7B. Carbohydrates and Glycobiology. Monosaccharides and Disaccharides Polysaccharides Glycoconjugates: Proteoglycans, Glycoproteins, and Glycosphingolipids Carbohydrates as Informational Macromolecules: the Sugar Code Working with Carbohydrates.

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Medical Biotechnology Regenerative Medicine

Medical Biotechnology Regenerative Medicine. Muhammad Adeel Faiza Asghar Amina Shakarullah. Focus Areas. What is Regenerative Medicine? Adeel What is the Current Perspectives and Therapeutic Potential of Regenerative Medicine? Amina A case study of Regenerative Medicine. Faiza.

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Fibroblast Growth Factor 3 (FGF3) int-2

Fibroblast Growth Factor 3 (FGF3) int-2. Brandon Williams. 3/25/03. OBJECTIVES. Biochemical Information Normal Function in Mouse Ear Development Breast Cancer and FGF3. EASY FACTS. 22 FGFs in vertebrates FGF3: Chromosome 11 (humans) Fgf3: Chromosome 7 (mice)

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Cell Surface Heparan Sulfate Proteoglycans

COOH. CH 2 OX. O. O. O. OX. OH. O. O. OX. NHY. GF. GF. Growth factor receptor. -P. P-. kinase. Signalling pathways. Cell Surface Heparan Sulfate Proteoglycans. Cells adapt structures of surface HS chains in response to their environment. A rapid method for sequencing HS

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Chapter 16, Figure 9

Heparan sulfate proteoglycans turn over by proteolytic shedding from the cell surface and endocytosis, as well as step-wise degradation inside lysosomes. Essentials of Glycobiology . Chapter 16, Figure 9. Second Edition.

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Chapter 41, Figure 3

Degradation of heparan sulfate (HS). Essentials of Glycobiology . Chapter 41, Figure 3. Second Edition.

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Chapter 35, Figure 4

Formation of complexes among heparan sulfate, FGF2, and FGFR. Essentials of Glycobiology. Chapter 35, Figure 4. Second Edition.

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FGF Family

The fibroblast growth factors are a family of cell signaling proteins that are involved in a wide variety of processes, most notably as crucial elements for normal development. Any irregularities in their function lead to a range of developmental defects.

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