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Dystrophin and the Extracellular Matrix

Dystrophin and the Extracellular Matrix

Dystrophin and the Extracellular Matrix. Eric Niederhoffer SIU-SOM. Protein domain structure Dystrophin glycoprotein complex Contraction unit Cytoskeletal linkages at sarcolemma Muscle proteins and disease Creatine kinase and CKI In situ staining and Western blots.

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485 views • 10 slides
Eric Niederhoffer SIU-SOM

Eric Niederhoffer SIU-SOM

A 4-year-old African boy is brought in by his adoptive parents who say that he has pain in his limbs and does not want to walk. A 40-year- old man complains of progressive exertional shortness of breath. How are CO 2 , NO, and O 2 processed and transported?. How is heme synthesized?.

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204 views • 9 slides
Eric Niederhoffer SIU-SOM

Eric Niederhoffer SIU-SOM

A 38-year-old woman is brought to the physician because of frequent falls, increasing confusion, and incontinence. How does ethanol ingestion cause nutrition problems?. Eric Niederhoffer SIU-SOM. Ketone body processing overview Ketogenesis and ketone body utilization Clinical features.

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232 views • 7 slides
Eric Niederhoffer SIU-SOM

Eric Niederhoffer SIU-SOM

What is the role of the pentose phosphate pathway?. Eric Niederhoffer SIU-SOM. NADPH production Glutathione reduction (E), fatty acid/cholesterol synthesis (L) Glycolytic intermediates Fructose-6-phosphate, glyceraldehyde-3-phosphate Ribose-5-phosphate

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205 views • 6 slides
Biochemistry in SSB

Biochemistry in SSB

Biochemistry in SSB. Inflammation - signals, receptors, therapeutic drugs Sensations - neurotransmitters, signal transduction Locomotion - neurotransmitters, muscle cytoskeleton Nutrition - metabolism, deficiency, toxicity

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283 views • 1 slides

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