'Early clinical trials' presentation slideshows

1.2k views • 78 slides

Building better clinical trials : A perspective from a cell therapy trialist (and dean)

Building better clinical trials : A perspective from a cell therapy trialist (and dean). PRESENTED BY ROBERT D. SIMARI, M.D. 2 year f/up: 1 cardiac death in BMC group 0 deaths in PL group. JAMA 2013, Circ Res 2018. f/up: 0 deaths in BMC group

453 views • 45 slides

Re-Examination of the Design of Early Clinical Trials for Molecularly Targeted Drugs

Re-Examination of the Design of Early Clinical Trials for Molecularly Targeted Drugs. Richard Simon, D.Sc. National Cancer Institute linus.nci.nih.gov/brb. Objectives of Phase I Trials. Develop dose/schedule Determine whether the drug inhibits the targeted pathway. Dose/Schedule.

467 views • 32 slides