'Cd28' presentation slideshows

PLC activation Ca++ flux NF-AT / NFkB nuclear localization protein tyrosine phosphorylation

333 views • 22 slides

CTLA-4/CD28 Signaling Pathway

CD28 is the best characterized and most effective co-stimulatory molecule expressed by naive and primed T cells. CD28 is a 44-kDa glycoprotein that binds to B7-1 (CD80) and B7-2 (CD86) on antigen-presenting cells (APCs) CD28 might be associate, in its unphosphorylated state, with the serine/threonine protein phosphatase 2A (PP2A).

20 views • 1 slides