Carcinogenicity - PowerPoint PPT Presentation

The Future of Chemical Toxicity Testing in the U.S.

The Future of Chemical Toxicity Testing in the U.S. Toxicity Testing in the 21 st Century June 21, 2010 David Jacobson-Kram, Ph.D., DABT Office of New Drugs, CDER, FDA. Risk Assessment: Pharmaceuticals vs. Environmental Contaminants.

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Istituto Superiore di Sanita’

Istituto Superiore di Sanita’. Istituto Superiore di Sanita’ Rome Italy OpenTox Scientific Responsible: Romualdo Benigni rbenigni@iss.it. http://ecb.jrc.it/documents/QSAR/EUR_22772_EN.pdf. Toxtree 1.51 Rulebase for mutagens / carcinogens. Structure-based approach consisting of:

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Discussion:

Discussion: I found that many authors do not believe that chromium-6 via oral exposure causes cancer.

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