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Back extrapolation - PowerPoint PPT Presentation

Time Plasma Conc (hr) (mg/L) 1 19. 5 2 14.4 5 5.8 8 2. 4 12 0.7 18 Below limit of detection

1 Compartment IV Analysis & Renal Elimination. 500 mg of tobramycin is administered by iv bolus to Mr BB, a 68 yr old male who weighs 75 kg. Blood samples were drawn following the dose and the plasma concentration determined. It is known that tobramycin is excreted primarily unchanged in

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Back extrapolation - PowerPoint PPT Presentation

Time Plasma Conc (hr) (mg/L) 1 19. 5 2 14.4 5 5.8 8 2. 4 12 0.7 18 Below limit of detection