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Topic #7 Single-Locus Association Studies: Case-Control Studies

Topic #7 Single-Locus Association Studies: Case-Control Studies. University of Wisconsin Genetic Analysis Workshop June 2011. Outline. Case-Control Study: Two-allele, single locus model Alternative Tests for Association Quantitative Outcomes: Two-allele, single locus model

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Barbara Peil, Benjamin Meder, Monika Stoll, Hugo A. Katus and Justo Lorenzo Bermejo

Taking advantage of genotype imputation to detect the association between known risk variants and disease subphenotypes in dilated cardiomyopathy. Barbara Peil, Benjamin Meder, Monika Stoll, Hugo A. Katus and Justo Lorenzo Bermejo. Introduction.

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Lecture 20 - Association Tests

Lecture 20 - Association Tests. Gibson and Muse, Chapt. 3, 2nd Ed. Association Populations. Case-Control - unstructured populations Family-Based - structured populations Continuous variable - structured and/or unstructured. Pitfalls of Association Tests. Trait h 2

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