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INTRODUCTION TO HAEMATOPOIETIC STEM CELL TRANSPLANT(HSCT)

INTRODUCTION TO HAEMATOPOIETIC STEM CELL TRANSPLANT(HSCT)

INTRODUCTION TO HAEMATOPOIETIC STEM CELL TRANSPLANT(HSCT). INTRODUCTION. HSCT is an approved curative option for the treatment of malignant and non-malignant diseases. STEM CELLS. Are primitive and undifferentiated cells with the capacity of self-renewal.

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1.08k views • 82 slides
HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT) IMED 7190 - Medical Immunology Cindy Ellison, PhD, D(ABHI) Departments of

HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT) IMED 7190 - Medical Immunology Cindy Ellison, PhD, D(ABHI) Departments of

HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT) IMED 7190 - Medical Immunology Cindy Ellison, PhD, D(ABHI) Departments of Pathology and Immunology. Objectives: Review HLA basics: structure, function, nomenclature and typing methods.

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843 views • 58 slides
Transplant Rejection

Transplant Rejection

Transplant Rejection. Major Histocompatibility complex (MHC). Also known as Human Leukocyte Antigen (HLA) They are encoded cell surface molecules that are specialized to present antigenic peptide to T-cells. Controlled by Genes Located on Chromosome 6. Role of MHC.

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Immunology 2008 Lecture 23 Vaccination 5 November

Immunology 2008 Lecture 23 Vaccination 5 November

Immunology 2008 Lecture 23 Vaccination 5 November. TODAY Vaccination, Chap. 22 Genetic Control (no core notes). Natural Immunity to Smallpox ? Known since antiquity ? Recovery from disease leads to immunity (smallpox et al .)

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Eric S. Huseby et al, Cell (2005); Nature Immunol. (2007),

Eric S. Huseby et al, Cell (2005); Nature Immunol. (2007),

Specificity. Eric S. Huseby et al, Cell (2005); Nature Immunol. (2007), compared the T cells of normal mice, with mice genetically engineered to present only one type of peptide in their thymus.

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138 views • 6 slides

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