Ancestral sequences - PowerPoint PPT Presentation

Lecture 8. Phylogenetic Tree Reconstruction

Lecture 8. Phylogenetic Tree Reconstruction. The Chinese University of Hong Kong CSCI3220 Algorithms for Bioinformatics. Lecture outline. Phylogenetic tree reconstruction Problem definition Sequence-based methods Maximum parsimony Maximum likelihood Distance-based methods UPGMA

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Methods of Tree Reconstruction

Methods of Tree Reconstruction. Dan Graur. Molecular phylogenetic approaches: 1. distance-matrix (based on distance measures) 2. character-state (based on character states) 3. maximum likelihood (based on both character states and distances). DISTANCE-MATRIX METHODS

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Evolution of Amino Acid Frequencies in Proteins

Evolution of Amino Acid Frequencies in Proteins. Inferred Order of Introduction of Amino Acids into the Genetic Code. Extant Genetic Code. From: http://www.millerandlevine.com/Code-Table-Rect.html. Is not a “frozen accident” There must have been earlier version

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