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Aml1 runx1 - PowerPoint PPT Presentation

AML1/Runx1 and oncogenic transformation

AML1/Runx1 and oncogenic transformation. RUNT domain (DNA BINDING). Chr 21. Chr 8. 4 Nervy repressor domains. Translocation (8;21). In human myeloid leukemia =>. RUNT domain. 4 Nervy repressor domains. Lozenge Drosophila. Runt Drosophila. Runx D.rerio. Runx1 G.gallus.

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Aml1 runx1 - PowerPoint PPT Presentation

AML1/Runx1 and oncogenic transformation