'6 bisphosphate' presentation slideshows

Chapter 15 Principles of metabolic regulation: Glucose and glycogen

Chapter 15 Principles of metabolic regulation: Glucose and glycogen. 15.1 The metabolism of glycogen in animals 15.2 Regulation of metabolic pathways 15.3 Coordinated regulation of glycolysis and gluconeogenesis 15.4 Coordinated regulation of glycogen synthesis and breakdown

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Chapter 15 Principles of metabolic regulation: Glucose and glycogen

Chapter 15 Principles of metabolic regulation: Glucose and glycogen. 15.1 The metabolism of glycogen in animals 15.2 Regulation of metabolic pathways 15.3 Coordinated regulation of glycolysis and gluconeogenesis 15.4 Coordinated regulation of glycogen synthesis and breakdown

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Gluconeogenesis; Regulation of Glycolysis & Gluconeogenesis

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Glycolysis Glycolysis overview Reactions of Glycolysis 1- Hexokinase (Glucose Phosphorylation)

Glycolysis Glycolysis overview Reactions of Glycolysis 1- Hexokinase (Glucose Phosphorylation) - Glucokinase 2- PhosphoFructokinase (PFK-1) - Regulation of PFK-1 Oxidation of glyceraldehyde into 1,3 bisphosphoglycerate Phosphoglycerate Kinase: First ATP generation step

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Glycolysis Glycolysis overview Reactions of Glycolysis 1- Hexokinase (Glucose Phosphorylation)

Glycolysis Glycolysis overview Reactions of Glycolysis 1- Hexokinase (Glucose Phosphorylation) - Glucokinase 2- PhosphoFructokinase (PFK-1) - Regulation of PFK-1 Oxidation of glyceraldehyde into 1,3 bisphosphoglycerate Phosphoglycerate Kinase: First ATP generation step

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Carbohydrate anabolism

Carbohydrate anabolism. We have covered some aspects of carbohydrate catabolism: glycolysis, PPP, citric acid cycle, etc. and now we turn to carbohydrate anabolic pathways that utilize ATP and reducing power for biosynthesis (ATP used to make favorable reactions)

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Regulation of glycolysis

Regulation of glycolysis. Flux through biochemical pathways depends on the activities of enzymes within the pathway For some steps, the reactions are at or near equilibrium in the cell

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Glycolysis

Glycolysis. Glycolysis. The conversion of glucose to pyruvate to yield 2ATP molecules 10 enzymatic steps Chemical interconversion steps Mechanisms of enzyme conversion and intermediates Energetics of conversions Mechanisms controlling the Flux of metabolites through the pathway.

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GLUCONEOGENESIS

GLUCONEOGENESIS. Synthesis of glucose from noncarbohydrate precursors. Learning objectives: List gluconeogenic precursors List the enzymes and intermediates involved in gluconeogenesis List the irreversible and regulated steps of gluconeogenesis Discuss regulation of gluconeogenesis.

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Regulation of Metabolism Lecture 28

Regulation of Metabolism Lecture 28. How does the body know when to increase metabolism? Slow metabolism? What might be some indicators of energy status within the cell?. Requires communication. Works through allosteric regulation of enzyme activity. Mechanisms of Cellular Communication.

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Regulation of Metabolism Lecture 28

Regulation of Metabolism Lecture 28. How does the body know when to increase metabolism? Slow metabolism? What might be some indicators of energy status within the cell?. Requires communication. Works through allosteric regulation of enzyme activity. Mechanisms of Cellular Communication.

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Regulation of Metabolism Lecture 28-Kumar

Regulation of Metabolism Lecture 28-Kumar. How does the body know when to increase metabolism? Slow metabolism? What might be some indicators of energy status within the cell?. Requires communication. Works through allosteric regulation of enzyme activity.

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Gluconeogenesis

Gluconeogenesis. Anabolic pathway that makes glucose from pyruvate Net result = reverse of glycolysis Three topics: 1. Thermodynamics 2. Enzymes 3. Regulation. Gluconeogenesis. 1. Thermodynamics

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DENTAL BIOCHEMISTRY 2015 LECTURE 10 GLUCONEOGENESIS

DENTAL BIOCHEMISTRY 2015 LECTURE 10 GLUCONEOGENESIS. Michael Lea. Lecture Outline. Function of gluconeogenesis and tissue distribution Reaction sequence Rate-limiting steps Energy requirement Substrates and regulation of gluconeogenesis

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ENERGY-INVESTMENT STAGE

C. C. C. C. C. C. ENERGY-INVESTMENT STAGE. Glucose. ATP. Step 1 . Glucose is phosphorylated by ATP to form glucose 6-phosphate. 1. ADP. C. C. C. C. C. C. P. Glucose 6-phosphate. C. C. C. C. C. C. ENERGY-INVESTMENT STAGE. Glucose. ATP.

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