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A-1331852 - CAS 1430844-80-6

A-1331852 - CAS 1430844-80-6

A-1331852, a substituted benzothiazole, is a high affinity BH3 mimetic Ligand of BCL protein BCL-XL (Kiu2264 10 pM). A-1331852 is an orally apoptosis-inducing agent that may have potential as improved cancer therapeutics.

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CPI-444

CPI-444

tCPI-444 is a potent, orally available, selective antagonist of the adenosine A2A receptor that has been well tolerated in Ph 1/1b studies in non-oncology indications.

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CPI-444

CPI-444

CPI-444 is a potent, orally available, selective antagonist of the adenosine A2A receptor that has been well tolerated in Ph 1/1b studies in non-oncology indications.

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GSK2193874

GSK2193874

tGSK2193874 is a potent, orally active and specific antagonist of TRPV4 ion channels (IC50 values 2 and 40 nM for rat and human receptors, respectively). GSK2193874 is selective over a panel of ~200 human receptors, channels and enzymes.

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GSK2982772

GSK2982772

tGSK2982772, with potential effect to treat inflammatory diseases, potently binds to RIP1 with exquisite kinase specificity. In phase 2a clinical studies for psoriasis, rheumatoid arthritis, and ulcerative colitis.

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MSC2530818

MSC2530818

tMSC2530818 is a specific and orally available CDK8 Inhibitor with an IC50 of 2.6 nM for CDK8.

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Esomeprazole Impurity 22

Esomeprazole Impurity 22

tEsomeprazole Impurity 22 is an impurity of Esomeprazole. Esomeprazole is the (S)-(u2212)-enantiomer of omeprazole, a medication of the proton pump inhibitor class used for the treatment of gastroesophageal reflux disease (GERD) and gastric ulcer.

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3'-Hydroxypropiophenone

3'-Hydroxypropiophenone

t3-HYDROXY PROPIOPHENONE; 3'-HYDROXYPROPIOPHENONE; 1-(3-hydroxyphenyl)propan-1-one

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5,6-Dimethoxy-2-(piperidin-4-ylmethyl)-2,3-dihydroinden-1-one

5,6-Dimethoxy-2-(piperidin-4-ylmethyl)-2,3-dihydroinden-1-one

tAn impurity of Donepezil, a medication for the treatment of Alzheimer's disease.

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BLU-554

BLU-554

BLU-554 is a potent and selective inhibitor of fibroblast growth factor receptor 4 (FGFR4) (IC50 = 5 nM), which is promisingly to be used for the treatment of hepatocellular carcinoma and cholangiocarcinoma.

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disodium 6-[(2,4-dimethyl-6-sulphonatophenyl)azo]-5-hydroxynaphthalene-1-sulphonate

disodium 6-[(2,4-dimethyl-6-sulphonatophenyl)azo]-5-hydroxynaphthalene-1-sulphonate

1-Naphthalenesulfonic acid, 6-[2-(2,4-dimethyl-6-sulfophenyl)diazenyl]-5-hydroxy-, sodium salt (1:2)

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Epsilon-polylysine

Epsilon-polylysine

epsilon-Polylysin; Polylysine

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ICEC-0942

ICEC-0942

tICEC-0942 is a small-molecule cyclin-dependent kinase 7 (CDK7) inhibitor developed for cancer therapy. Preclinical study in Acute Myeloid Leukaemia (AML) models shows that ICEC-0942 effectively inhibits the proliferation of several AML cell lines and patient derived AML cells in vitro (IC50 = 0.15-2.6 u03bcM).

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Marmesinin

Marmesinin

tAmmijin; (-)-Marmesinin; (S)-2-(1-(beta-D-Glucopyranosyloxy)-1-methylethyl)-2,3-dihydro-7H-furo(3,2-g)(1)benzopyran-7-one

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Hordenine

Hordenine

Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties.

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[D-Ala2]-Leucine enkephalin

[D-Ala2]-Leucine enkephalin

t[D-Ala2]-Leucine enkephalin is a delta opioid agonist used to study the signaling pathway of delta opioid receptors.

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Cucurbitacin A

Cucurbitacin A

Cucurbitacin A is a triterpenoid sterol isolated from rhizomes of Hemsleya amabilis Diels.

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Calycanthine

Calycanthine

tCalycanthine is an alkaloid isolated from seeds of Chimonanthus praecox. Calycanthine exhibits potent antifungal activity against five plant pathogenic fungi including Exserohilum turcicum, Bipolaris maydis, Alternaria solani, Sclerotinia sderotiorum and Fusarium oxysportium.

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Seleno-L-cysteine

Seleno-L-cysteine

tNutritional supplement; dietary supplements; health food additives; sport nutrition; sport supplements; bodybuilding supplement; pharmaceutical raw material; As a building block of selenoproteins

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Protein hydrolyzates, yeast

Protein hydrolyzates, yeast

t3',6'-bis(diethylamino)-6-isothiocyanato-3h-spiro[2-benzofuran-1,9'-xanthen]-3-one; 3',6'-BIS(DIETHYLAMINO)-6-ISOTHIOCYANATO-3H-SPIRO[2-BENZOFURAN-1,9'-XANTHENE]-3-ONE; RhodamineB-5(or6)-isothiocyanate; AC1Q7EVJ; AC1L3B4G; AR-1E9925

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