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Spectrophotometric determination of 6-(trifluoro methyl) furo [2,3-b] pyridine-2- carbohydrazide derivatives as antioxid

Spectrophotometric determination of 6-(trifluoro methyl) furo [2,3-b] pyridine-2- carbohydrazide derivatives as antioxid

A novel Antioxidant study of 6-(trifluoro methyl) furo [2, 3-b] pyridine-2- carbohydrazide derivatives, a sensitive spectrophotometric method was employed. The method is based on the reaction of these drugs as n-electron donors with the pi-acceptor 2,3,5,6-tetra chloro 1,4-nenzo quinone. The obtained coloured charge-transfer complex was measured at 440nm. The obtained complexes were confirmed by using the 1HNMR and IR spectral analysis. The proposed procedure could be applied successfully to the determination of the Free radical Scavenging activity of the title compounds. Among the Twelve analogs, V3 exhibited highest antioxidant activity and very low IC50 value. The association constants and standard free energy changes using Benesi-Hildebrand plots were studied.

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127 views • 7 slides
Preparation and Evaluation of Antimicrobial Herbal based Incense Sticks for Fumigation aga

Preparation and Evaluation of Antimicrobial Herbal based Incense Sticks for Fumigation aga

A series of some new 2,2'(2,5-dimethoxy-3,6-dioxocycloxa-1,4-diene-1-4-diyl)bis(azanediyl) diacetic acid analogues were synthesized with the objective for evaluation as antimicrobials. Reaction of 2,5-dibromo-3,6-dimethoxy-1,4- benzoquinone with amino acids in the presence of triethylamine in ethanol gave the corresponding title compounds. The structures of all the newly synthesized compounds have been supported by elemental analysis, IR, 1H NMR and mass spectral data. All the synthesized compounds were tested for their antibacterial activity in comparison with the standard drug Streptomycin.

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United States 1,4-Benzoquinone Market Revenue, Share and Growth Rate to 2025

United States 1,4-Benzoquinone Market Revenue, Share and Growth Rate to 2025

United States 1,4-Benzoquinone Market is expected to grow at a significant CAGR in the upcoming years as the scope, product types and its applications are increasing across the globe.

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44 views • 4 slides

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