Laboratory of Immunobiochemistry. Research update. Active research projects. PI Slater Cockroach allergen standardization Determination of optimal surrogate test Depletion analysis of CR extracts Cockroach IgE/IgG combinatorial library Microarray analysis of allergen extracts
Trivedi B, Valerio C, Slater JE. Endotoxin content of standardized allergen vaccines. J Allergy Clin Immunol 2003; 111:777-783.
Lockey RF, Slater JE, Esch R. Preparation and standardization of allergen vaccines. In Middleton’s Allergy: Principles and Practice, 6th ed. St. Louis: Mosby 2003;573-584.
Rabin RL, Alston MA, Sircus JC, Knollmann-Ritschel B, Moratz C, Ngo D, Farber JM. CXCR3 is induced early on the pathway of CD4+ T cell differentiation and bridges central and peripheral functions. J Immunol. 2003;171:2812-24.
Zhang J, Alston MA, Huang H, Rabin RL. Multidrug Resistant Protein 1 (MRP1) is induced upon activation of human T cells, and its inhibition blocks T cell function, in preparation
Valerio C, Murray P, Arlian LG, Slater JE. Endotoxin in dust mite allergen extracts. J Allergy Clin Immunol 2004; S136
Gam AA, Slater JE. Depletion of Specific Cockroach Allergens May Not Affect Overall Allergenicity Determinations. J Allergy Clin Immunol 2004; S144
Finlay WJJ, Dobrovolskaia EN, Gam A, Slater JE. Generation of mono-specific recombinant antibody fragments from chicken to allergenic proteins Fel d 1, Amb a 1 and whole yellow jacket venom. J Allergy Clin Immunol 2004; S227
deVore N, Finlay W, Dobrovolskia E, Gam A, Slater J. Cloning and Analysis of Mono-specific scFv Fragments from Chicken to Allergenic Proteins of Periplaneta americana (American Cockroach). J Allergy Clin Immunol 2004; S297
Alston MA, Zhang J, Huang H, Rabin RL. The Drug Pump Multi-Drug Resistance Protein 1 (MRP1) is Induced upon T cell Activation and its Inhibition Blocks T cell Function. J Allergy Clin Immunol 2004; S249
Chi B, Spann KM, Collins PL, Rabin RL. T Cell Response to Respiratory Syncytial Virus (RSV). J Allergy Clin Immunol 2004; S269
State of the Art Analytical Methods for the Characterization of Biological Products and Assessment of Comparability, June 2003:
Director, Microbiology and Immunology, Department of Biological Sciences, Wright State University, Dayton, Ohio
Patrick R. Murray, PhD
Chief, Microbiology Service, NIH Clinical Center, Bethesda, Maryland
Peter L. Collins, PhD
Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland
Mario Roederer, PhD
Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MarylandOutside collaborations
fD1 (most eubacteria):
rP1 (most eubacteria):
From Weisburg, J. Bacteriol. 1991; 172:697-703
Matera et al., Int Immunopharmacol 2003; 3:853-864
Zahringer et al., J Biol Chem 2004 (Epub)