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p85

RTKs (EGFR, HER2, FGFR, IGFR, c-MET). AKT Inhibitors MK-2206, XL418, GDC-0068 , AR-67, GSK690693, VQD-002. PDK1 Inhibitors AR-12, UCN-01. PI3K. p85. p110. IRS1. PIP2. PDK1. PIP3. Src. mTOR-rictor. Akt. Dual PI3K/mTOR Inhibitors BEZ235, XL765, GDC-0980, GSK1059615

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p85

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  1. RTKs (EGFR, HER2, FGFR, IGFR, c-MET) AKT Inhibitors MK-2206, XL418, GDC-0068, AR-67, GSK690693, VQD-002 PDK1 Inhibitors AR-12, UCN-01 PI3K p85 p110 IRS1 PIP2 PDK1 PIP3 Src mTOR-rictor Akt Dual PI3K/mTOR Inhibitors BEZ235, XL765, GDC-0980, GSK1059615 PanPI3K Inhibitors BKM120, GDC-0941, BAY 80-6946, SF1126, PX-866, XL147, CH5132799, GSK1059615 Isoform selective PI3K Inhibitors BYL719, MLN1117, TGX-221, GSK2636771, CAL101 mTORC1/2 Inhibitors OSI-027, AZD-8055, PP-242, INK-128 PTEN GSK3 TSC1/2 mTOR-raptor FOXO MDM2 S6K 4E-BP1 C-Myc, Cyclin D1 FasL, Bim p27Kip1 p21 p53 BAD eIF4E rpS6 Cell Survival Proliferation Metabolism Protein Synthesis

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