Introduction. Previously, the role of fungi as significant pathogens: endemic mycoses Review of world literature by Hurley in 1964: only 48 cases of disseminated candidiasisSince the 1980\'s: Increase in opportunistic fungal infections. LET\'S HAVE A PARTY. Fungemia at UHWI. 1998: 131999:122001:152002: 292003: 27 (so far)USA: Nosocomial candidemia: 500% increase in 1980\'s in some places.