Sickle Cell Anemia. Chisom Amaefuna Adeline Laurente 1/29/10 Period 2. Summary. Sickle cell anemia is a genetic blood disease due to an abnormal form of a hemoglobin. Hemoglobin is the molecule in the red blood cell that transports oxygen from lungs to the farthest parts of the body
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
Sickle Cell Anemia is located in
-Sickle cell is inherited in an Autosomal recessive pattern.
-autosomal recessive-Genetic condition that appears only in individuals who have received two copies of an autosomal Gene
-The gene is on an autosome, a nonsex chromosome
-People with one defective gene and one normal gene are carriers
25% SS: 50% Ss: 25% ss
S SS Ss
s Ss ss
What is in the GENES
S represents dominant allele GREEN
s represents recessive allele yellow
SS=homozygous dominant (GREEN)
Ss= heterozygous dominant (GREEN)
ss= homozygous recessive (yellow)
25%: 50% : 25%
Normal to carrier to affected
What you can SEE
Ss= Green (yellow gene carrier)
Normal to affected
1SS: 2Ss: 1ss
SS 25%: Ss 50%: ss 25%
3 normal: 1 affected
75% normal: 25% affected
Ratio: 4 carriers
Percentage: All children will be carriers but not affected
1. Why don’t any of the second generation children have full sickle cell anemia?
2. How many people in this pedigree are carriers of sickle cell anemia?
3. How many people in this pedigree show no symptoms of sickle cell anemia?