Main Menu. 17.5 The Wittig and Related Reactions. The Wittig Reaction (formation of alkenes). General Reaction:. R´ and R” can be H or alkyl group. Phosphine oxide. Wittig reagent (a phosphonium ylide ). General Reaction:. base. Formation of Wittig Reagents. A phosphonium salt.
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17.5 The Wittig and Related Reactions
The Wittig Reaction
(formation of alkenes)
R´ and R” can be H or alkyl group.
Wittig reagent (a phosphoniumylide)
A phosphonium salt
Wittig reagents favor the Z (cis) isomer.
R = Et (most common)
Arbuzov (Perkow) reaction:
R = alkyl, acyl or R’OC(O)-
Horner-Emmons reagents favor the E (trans) isomer.
1. What could be the reagent for the following transformation?
2. What should be the product from the following reaction?
Main Menu transformation?
3. What could be the product for the following reaction?