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NEXTILLO_ #DIBS BY NEXTILLO DAILY INFORMATION BULLETIN SERVICE INTERMEDIATE UVEITIS NEXTILLO.COM
#DIBSBYNEXTILLO DAILY INFORMATION BULLETIN SERVICE INTERMEDIATE UVEITIS Intermediate uveitis refers to inflammation of pars plana, peripheral retina, choroid, and vitreous. NEXTILLO.COM
VISUAL REPRESENTATION NEXTILLO.COM
ETIOLOGY Idiopathic: 85% are idiopathic, though a genetic predisposition (HLA-DR2) may be involved. Known causes (15%): Includes tuberculosis, syphilis, sarcoidosis, Lyme disease, and multiple sclerosis. NEXTILLO.COM
CLINICAL FEATURES SYMPTOMS Floaters (spots or cobwebs in the vision) are the most common presentation, usually appearing gradually. Blurry vision or reduced vision may develop later. Pain, redness, and photophobia (light sensitivity) are usually absent. SIGNS Anterior segment: Often appears quiet Low-grade flare and cells Few keratic precipitates (KPs) Posterior segment: Snowball or cotton-ball opacities (also known as Ant's eggs), Inflammatory exudate floating in vitreous. Snow banking: A hallmark of intermediate uveitis (Inflammatory fibro vascular plaque/membrane on pars plana seen inferiorly) NEXTILLO.COM
INVESTIGATION Ocular: USG scan, FFA for CME Systemic: hemogram, LFT, KFT, Chest or spine x- ray, blood glucose, HIV, VDRL, CT of brain & spinal cord. NEXTILLO.COM
TREATMENT A 4-step treatment is commonly followed: Periocular and Systemic Steroids: Topical steroids are generally not effective. Intravitreal steroids: triamcinolone (40 mg every 3 weeks for 3 doses). If unresponsive, systemic steroids are used. Immunosuppressive Drugs: Methotrexate, cyclosporine, tocilizumab in children Cryotherapy or Laser Photocoagulation: If snow banking is present, cryotherapy or indirect laser photocoagulation Pars Plana Vitrectomy: Decreases the inflammation After the procedure patient start responding to steroids. NEXTILLO.COM
MCQ QUESTION: A 28-year-old male presents with complaints of blurred vision in both eyes, floaters, and occasional flashes of light for the past 3 weeks. On examination, the patient has vitreous cells and snowbanking at the retinal periphery. There is no involvement of the anterior chamber. What is the most likely diagnosis? A) Intermediate Uveitis B) Retinal Detachment C) Posterior Uveitis D) Diabetic Retinopathy Answer: A) NEXTILLO.COM