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NEXTILLO_ #DIBS BY NEXTILLO DAILY INFORMATION BULLETIN SERVICE BROWN-SEQUARD SYNDROME NEXTILLO.COM
#DIBSBYNEXTILLO DAILY INFORMATION BULLETIN SERVICE BROWN-SEQUARD SYNDROME Brown-Sequard Syndrome is a hemi- section (one-sided injury) of the spinal cord, leading to distinct ipsilateral and contralateral neurological deficits. NEXTILLO.COM
#DIBSBYNEXTILLO DAILY INFORMATION BULLETIN SERVICE CAUSES Trauma (stab wounds, gunshot injuries) Spinal cord tumors Multiple sclerosis Disc herniation Ischemia (Spinal stroke) NEXTILLO.COM
VISUAL REPRESENTATION NEXTILLO.COM
CLINICAL FEATURES NEXTILLO.COM
KEY MNEMONIC: “IPSILATERAL MVP” M - Motor loss (Corticospinal) V - Vibration & Proprioception loss (Dorsal column) P - Pain & Temperature loss on opposite side (Spinothalamic) Diagnosis MRI Spine (gold standard) CT Myelography NEXTILLO.COM
TREATMENT Address underlying cause (e.g., trauma stabilization, Tumor removal) Steroids (if inflammation present) Physical therapy & rehabilitation NEXTILLO.COM
CLINICAL CASE A 35-year-old male is brought to the emergency department after being stabbed in the right side of his lower back. On examination: He has weakness and loss of proprioception in his right leg. He has loss of pain and temperature sensation in his left leg, starting a few segments below the injury. Deep tendon reflexes are reduced on the right side below the lesion. The left side retains motor function and proprioception. NEXTILLO.COM
MCQ QUESTION: Which of the following best explains this patient’s condition? A) Complete spinal cord transection B) Central cord syndrome C) Brown-Sequard syndrome D) Anterior spinal artery syndrome Answer: C) Brown-Sequard Syndrome NEXTILLO.COM
Explanation: The patient has ipsilateral motor weakness and proprioception loss (right side) and contralateral pain & temperature loss (left side), which is characteristic of Brown-Sequard Syndrome. Pathophysiology ·Corticospinal tract (motor): Crosses at the medulla - Ipsilateral weakness below the lesion. ·Dorsal column (proprioception, vibration): Crosses at the medulla - Ipsilateral loss below the lesion. ·Spinothalamic tract (pain & temperature): Crosses at the spinal level 1-2 segments above - Contralateral loss below the lesion. NEXTILLO.COM
Incorrect A) Complete spinal cord transection - it may cause bilateral motor and sensory loss. B) Central cord syndrome - More common in elderly with hyperextension injuries and affects upper limbs more than lower. D) Anterior spinal artery syndrome -Affects bilateral motor and pain/temperature sensation but spares proprioception. NEXTILLO.COM