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Urinary System - PowerPoint PPT Presentation


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Urinary System . Introduction • The urinary system Filters the body of waste materials , Homeostaticaly regulates bodys fluid status,electrolyte balance and acid base balance. Endocrine and Synthetic functions. EPO Controls RBC production from stem cells in marrow

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slide1

Urinary System

Introduction

• The urinary system Filters the body of waste materials ,Homeostaticalyregulates bodys fluid status,electrolyte balance and acid base balance.

Endocrine and Synthetic functions

  • EPO
    • Controls RBC production from stem cells in marrow
    • Stimulated by reduced PO2 in kidney (not systemic PO2)
  • Vitamin D
    • Active form (calcitrol) produced by a hydroxlation in kidney & liver
    • Important for calcium absortion from GI and also neuronal development in-utero
  • Renin
    • An enzyme. Synthesized in juxtaglomerular (granular) cells in afferent arteriole
    • Stimulated by a fall in circulating volume
    • Leads to the production of Ang II and Aldosterone
slide2

Basic Anatomy of the Kidney

Renal Hilus:

Renal artery, vein, nerves, lymphatics & renal pelvis

Cortex

Medulla:

Renal Pyramids

Medullary rays

Papilla

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Nephron Structure: Associated Blood Vessels

Renal → segmental → interlobar → arcuate → cortical radial (interlobular) → afferent → glomerulus → efferent

Two arterioles and two capillary beds in series

The Kidney Has The Highest Blood Flow Per Unit Mass Among Major Organs.

1250 ml/min = 25% of cardiac output