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Signs of Life The Biotech Industry in D.C. Heike Mayer & Alan Fogg Assistant Professor Graduate Student Urban Affairs and Planning Master of Urban and Virginia Tech – Alexandria Center Regional Planning. Roadmap. Introduction to Biotech Industry

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Signs of life the biotech industry in d c l.jpg

Signs of LifeThe Biotech Industry in D.C.

Heike Mayer & Alan Fogg

Assistant Professor Graduate Student

Urban Affairs and Planning Master of Urban and Virginia Tech – Alexandria Center Regional Planning


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Roadmap

  • Introduction to Biotech Industry

  • Key Findings- Nation (Brookings Study 2002)- Regional update

  • Key Lessons


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Why Biotech?

 The next Silicon Valley

 The battle for the Dot.Coms

 Next Big Thing: Biotech

  • 83% of local development agenciesplace bio among their top two priorities

  • 41 States have biotech programs

     Next next thing? Nanotech, Bio IT ?


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Definitions & Methods

  • Biotechnology

    • Firms using genetic and cellular techniques

    • Biomedicine: diagnostic/therapeutic

    • Industry-developed definitions & data

  • Top 51 Metropolitan Areas

    • Census-defined CMSA/PMSA list

  • Triangulation of data sources:Research & Commercialization


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Pharmaceutical

Very large, global firmsTop ten average $15 bio sales

Assets are products, distribution, manufacturing expertise

Very profitable

Industry Segmentation

Biotechnology

Small, mostly single establishment firmsTop ten average $700 mio sales

Principal assets are people, research and future potential

Lose money


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Nine Metros Dominate

Seattle

Boston

New York

Philadelphia

San Francisco

Why these nine?

Washington-Baltimore

Los Angeles

Research Triangle Park

San Diego


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NIH Grants

Patents

Venture Capital

R&D Partnerships

Startup Firms

Established Firms

Pillars of Biotech Development

Research

Commercialization


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Leaders vs. the Pack

Average Levels of Activity


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Research Dispersing

1980s 1990s

NIH $ 63% 59%

Patents 71% 68%

Top 9 Centers Share


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Commercialization Concentrating

1980s 1990s

Venture Capital* 81% 86%

R&D Alliances* 89% 96%

New Firms 61% 77%

*Base data from early to mid-1990s

Top 9 Centers Share


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NIH Funding

Research Grants, 2000 (Millions)

3rd


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Biotech Related Patents

Patents Awarded, 1990-1999

5th


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Venture Capital

Investment, 1995-2001 (Millions)

9th


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R&D Alliances

Value of R&D Alliances, 1996-2001 (Millions)

6th


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Biotech Startups

New Biotech Firms Started Since 1990

6th


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Established Biotech Companies

Firms with 100 or more employees

4th


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Washington/Baltimore Cluster

  • Research Assets

    • Johns Hopkins, NIH

  • Cadre of Biotech Firms

    • Human Genome Sciences, Celera, Med-Immune, Alpharma, Genvec, Neurologic, Macrogenics

    • Dozens of others in biotech & related fields

  • BIO: National Industry Association


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Washington/Baltimore Cluster

  • Clearly among the top 9

  • Very strong in research

    • High levels of NIH funding

    • High volume of patents

  • Not as strong in commercialization

    • $85 million in venture capital

    • $17 million in R&D alliances with big Pharma

    • Heavily concentrated in Rockville-Gaithersburg


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NIH Grant Awards

Millions of Dollars


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NIH Grant Awards by Sub-Region

Millions of Dollars


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NIH Grant Awards: Virginia

Major recipient communities

in Virginia:

Richmond

Charlottesville

Blacksburg


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Employment

Washington MSABaltimore MSA

Note: NAICS 54170 includes R&D in Social Sciences


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Number of Firms

Note: Includes NAICS 3254 and NAICS 54170 (includes R&D in Social Sciences)


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VC Investment: DC/Metroplex

Millions of Dollars

Maryland

D.C.

Virginia


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Biotech initiatives – Maryland

  • University of Maryland, Baltimore, opens $300 million BioPark

  • East Baltimore Biotech Park ($200 mio project; will house 30 to 50 companies; urban redevelopment)

  • Baltimore Development Corp. opens two Emerging Technology Centers (one near JHU) for bio and IT companies

  • University of Maryland College Park and University of Maryland Biotechnology Institute launch educational and research initiatives in nano-biotechnology and molecular bioprocessing

  • Maryland Department of Business and Economic Development (DBED) and Technology Development Corporation (TEDCO) fund early-stage companies

  • Townsend Capital of Towson launches a company to develop science- and technology-related projects with universities and health care systems


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Biotech initiatives – Virginia

In Northern Virginia

  • $500 million Howard Hughes Medical Institute campus (Janelia Farm) to open in Loudoun County

  • Eli Lilly to open plant in Prince William County

  • George Mason University awarded $25 million grant (largest in school history) from the National Institute of Allergy and Infectious Diseases for construction of a Regional Biocontainment Laboratory at its Prince William campus.

  • George Mason and Italian institute sign a three-year agreement to develop proteomics research program to unveil cancer diagnostics and therapies

    And in Richmond:

  • Philip Morris USA to build $300 million research and development facility at the Virginia Biotechnology Research Park in Richmond


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Lessons from this region

  • The share of biotech employment in the overall economy is very small (~1.5 %)

  • Biotech is heavily concentrated in MD

  • Maryland ahead in commercialization

  • Baltimore MSA may become a leader

  • Strong & pro-active economic development environment in MD

  • D.C. and VA portion of metro need to focus on gaining in research, but even more so in commercialization

  • Potential to link to other economic strengths (such as homeland security, IT, telco, etc.)??


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General lessons

  • Biotech tends to cluster (even sub-regionally)

  • Leaders have an edge (commercialization)

  • Entrepreneurship & VC are key- Entrepreneurial researchers- Industry-relevant talent- VC

  • “Bottom 42” -> hard to catch up

  • Modest payoff- No biotech firm among 25 largest employers- Averages about 3.5 % of manufacturing empl.- Most firms stay small


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Thank You!

Questions, Comments, Suggestions…

Heike Mayer

Virginia Tech

Phone: 703.706.8122

E-Mail: heikem@vt.edu

Brookings Publication:

Cortright, J., & Mayer, H. (2002). Signs of life: The growth of biotechnology centers in the U.S. Washington DC: The Brookings Institution.

Link: www.brookings.edu/es/urban/publications/biotech1.pdf