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Evolution of Germ Theory in Medicine: Milestones and Discoveries

Explore the historical journey of germ theory in medicine from the works of pioneering scientists like Pasteur, Koch, to modern discoveries of HIV and cervical cancer-causing viruses. Understand Koch's postulates and their impact on disease understanding.

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Evolution of Germ Theory in Medicine: Milestones and Discoveries

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  1. Dr Ömer Küçükbasmacı

  2. 1647 Antonie van Leeuwenhook • Otto Müller • Ignaz Semmelweis • John Snow • Friedrich Henle “The germ theory of disease” 1840 • Louis Pasteur • Robert Koch

  3. Paul Ehrlich 1910 • Alexander Fleming 1928 • Gerhard Domagk 1935 • Selman Walkman 1943

  4. Koch's postulates are: • The microorganism must be found in abundance in all organisms suffering from the disease, but should not be found in healthy animals. • The microorganism must be isolated from a diseased organism and grown in pure culture • The cultured microorganism should cause disease when introduced into a healthy organism. • The microorganism must be reisolated from the inoculated, diseased experimental host and identified as being identical to the original specific causative agent.

  5. 2006 Robin Warren, Barry J. Marshall • Harald zur Hausen for his discovery of "human papilloma viruses causing cervical cancer" and the other half jointly to • Françoise Barré-Sinoussi and Luc Montagnier for their discovery of "human immunodeficiency virus"

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