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Analysis of FOXP3 and KIR Variants in Relapse-Free Survival: Insights from Fold Change Metrics

This study investigates the role of immune regulatory genes FOXP3, KIR3DL3, KIR2DL3, and KIR2DL2 in relapse-free survival rates. We present a detailed analysis of fold change data and p-values, revealing significant insights (p=0.02 for FOXP3) about their influence on relapse patterns. The survival risk function is explored over months, providing a timeframe for evaluating clinical outcomes. These findings enhance our understanding of predictive markers in immunological responses and their potential implications in therapeutic strategies.

rooney-franklin
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Analysis of FOXP3 and KIR Variants in Relapse-Free Survival: Insights from Fold Change Metrics

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  1. 10E-3 10E-4 10E-5 10E-6 A FOXP3 p=0.02 10E-5 10E-6 10E-7 10E-8 10E-9 KIR3DL3 10E-3 10E-4 10E-5 10E-6 10E-7 10-8 KIR2DL3 Fold change Fold change Fold change Relapse free Relapse 10E-3 10E-4 10E-5 10E-6 B KIR2DL3 KIR2DL2 Relapse free Relapse p=0.7 p=0.15 p=0.2 Fold change Relapse free Relapse Relapse free Relapse C Relapse Relapse free D CD1d p=0.2 Survival risk function 0.0 0.2 0.4 0.6 0.8 1.0 LFA1 0 20 40 60 80 100 Months

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