The Most Impactful And Visionary Personality To Look For in 2025

Vol 03 | Issue 04 | 2025 The Most Impactful and Visionary Personality to look for in 2025 IN FOCUS Emerging Visionary Personalities Making a Difference. IN FOCUS The Role of Visionary Leadership in a Rapidly Changing World Founder and President | Förderverein OrphanHealthcare Dr. Frank Grossmann Pioneering a Holistic Approach to Rare Disease Advocacy and Healthcare Innovation www.ciobusinessworld.com

The Most Impactful and Visionary Personalities to Watch in 2025 A s we move deeper into the digital age, leadership is no longer just about decision-making—it is about vision. The most impactful personalities of 2025 will not simply be those who achieve success, but those who redefine industries, challenge conventional thinking, and drive meaningful change. From tech pioneers to business leaders, from policymakers to cultural innovators, the individuals shaping the future are those who see beyond the present and create what comes next. center of corporate strategy. Visionary leaders of 2025 will be those who rethink workplace culture, ensuring that flexibility, inclusivity, and innovation drive productivity. Visionaries stand apart because they don’t just react to change—they anticipate it. They are the ones investing in artificial intelligence, reimagining sustainability, and revolutionizing the way we work and interact. As industries undergo rapid transformation, those who can merge technological advancement with human-centric leadership will be the ones to watch. These individuals recognize that talent is global and that the future workforce will demand more than just competitive salaries. They will champion mental health, prioritize work- life balance, and invest in skill development, ensuring that businesses remain agile in an ever-evolving world. The Rise of AI-Driven Leadership Leadership Beyond Titles Artificial intelligence is no longer a futuristic concept—it is here, actively reshaping business strategies, customer experiences, and even governance models. The most impactful personalities of 2025 will be those who understand how to harness AI responsibly, balancing efficiency with ethics. In 2025, the most impactful and visionary personalities will not necessarily be those with the highest positions or the biggest corporations. They will be those who lead with purpose, adapt to change, and inspire transformation. CIOs, business leaders, and entrepreneurs must keep an eye on these game-changers—not just to follow trends, but to actively participate in shaping the future alongside them. Because the real visionaries don’t just predict the future—they create it. Sustainability as a Business Imperative These individuals understand that environmental responsibility is not just about compliance—it is about long-term profitability and resilience. They are proving that sustainability and economic growth can coexist, setting a new benchmark for corporate leadership. Another key area where visionaries will lead is sustainability. With climate change becoming a pressing global concern, businesses can no longer afford to treat sustainability as a secondary priority. The most forward- thinking leaders of 2025 will be those embedding sustainable practices into the core of their business models—whether through renewable energy, circular economies, or carbon-neutral operations. These leaders are not just technologists; they are problem- solvers who recognize AI’s potential while mitigating its risks. They are shaping regulatory frameworks, advocating for ethical AI use, and integrating machine learning into industries in ways that enhance human potential rather than replace it. Their ability to guide AI-driven change will define their influence in the coming years. Redefining Work and Leadership The post-pandemic world has fundamentally changed how businesses operate. Hybrid work models, digital transformation, and employee well-being are now at the

P r o f i l e s C o v e r S t o r y 10 18 Aurélien Cuellar Director Technology Omnichannel Operations – Chalhoub Group Dr. Frank Grossmann Pioneering a Holistic Approach to Rare Disease Advocacy and Healthcare Innovation 22 Bernard Wanyama Navigating the Tech Landscape 30 Marc Lubner Showing how Leaders can drive Impact and Change A r t i c l e s 34 TopDigital Technologies Shaping Retail in 2024 28 38 Emerging Visionary Personalities Driving Change The Role of Leadership in a Changing World

Cover Story Dr. Frank Grossmann Pioneering a Holistic Approach to Rare Disease Advocacy and Healthcare Innovation “ Dr. Frank Grossmann Founder and President OrphanHealthcare “ I work across sectors to integrate ethical business practices, circular economy principles, and social entrepreneurship into the healthcare ecosystem. www.ciobusinessworld.com www.ciobusinessworld.com 10 | March 11 | March

D commitment. His life has been shaped by a deeply personal battle, one that ignited his passion to bridge the gaps in healthcare, drive patient advocacy, and pioneer sustainable solutions for rare disease communities. As the Founder and President of OrphanHealthcare, Dr. Grossmann has redefined what it means to be a healthcare entrepreneur, weaving together science, social responsibility, and technology to create a lasting impact. r. Frank Grossmann’s journey from being a rare disease patient to becoming a transformative leader in healthcare is a story of resilience, innovation, and unwavering A Journey Rooted in Personal Experience At just 12 years old, Dr. Grossmann was diagnosed with a rare cancer. The uncertainty and immense challenges that came with this diagnosis shaped his perception of life’s purpose. Against all odds, he was cured, but the road to recovery was arduous and transformative. This experience sowed the seeds for his lifelong commitment to healthcare innovation and patient advocacy. Unlike many who enter the healthcare field driven by academic pursuits alone, Dr. Grossmann’s mission is a unique and personal one. His firsthand understanding of what it means to be a patient fueled his drive to ensure that others navigating rare diseases would not feel alone or unsupported. responsibility.“ “ His career began with studies in veterinary medicine in Hanover and Sydney, leading after to a doctorate at the prestigious ETH Zurich and the University of Zurich. He later specialized in pharmacology and drug development, equipping himself with the expertise to understand the complexities of medical science. For over a decade, he worked as a lecturer in pharmaceutical science at ETH Zurich, while also gaining extensive experience in regulatory affairs, pharma development, and medical diagnostics. However, he soon realized that breakthrough solutions for healthcare required more than traditional industry approaches - they required an entrepreneurial vision that broke through existing silos and focused on the underserved with fresh ideas and tangible offerings I envision a world where healthcare is not just a service but a shared Building OrphanHealthcare: A Vision for Rare Disease Advocacy In 2010, Dr. Grossmann took a decisive step in reshaping the landscape of rare disease advocacy. He founded Orphanbiotec Ltd and the NGO OrphanHealthcare, Switzerland’s first hybrid organization dedicated to rare diseases. Unlike conventional charities, OrphanHealthcare is a patient-centered initiative that integrates research, advocacy, and sustainable healthcare solutions. Its mission is to bridge the gap between corporate social responsibility, patient advocacy, and medical innovation, ensuring that individuals living with rare diseases receive the support and visibility they deserve. Visit to His Excellency, the former President of Malta G. Vella, in 2023, together with the former First Lady of Malta, Michelle Muscat. www.ciobusinessworld.com www.ciobusinessworld.com 12 | March 13 | March

The early years were filled with challenges. Public awareness about rare diseases was minimal, and breaking into an industry where mainstream diseases took precedence required relentless determination. Dr. Grossmann worked tirelessly to educate not only the general public but also healthcare professionals and policymakers about the struggles faced by rare disease patients. His work gained recognition through prestigious awards, including the SEIF Award in 2012 and the Co- Nomination for the W.A. De Vigier Prize in 2014. These accolades reinforced his commitment to reshaping healthcare access and pushing for innovative, ethical solutions. International Rare Disease Day 2025 in February marked a significant milestone, allowing patients to access reliable information and support 24/7 and more efficiently. This initiative was made possible through a pro bono partnership with a leading AI company, demonstrating Dr. Grossmann’s ability to leverage corporate sponsorships for social impact. Recognizing the limitations of traditional donation-based funding, he pioneered a model that aligns corporate incentives with long-term healthcare solutions. The CSR partnership with Swiss Prime Site has further strengthened OrphanHealthcare's mission and will enable the NGO to establish its first European campus, “Point of Care 4 Rare”, at the new office site in 2025. This groundbreaking initiative serves as a hub for research, patient care, and advocacy, setting new standards for rare disease support. A Transformative Leadership Approach Dr. Grossmann’s leadership is defined by his ability to merge healthcare expertise with entrepreneurial innovation. His belief in corporate responsibility and cross-sector collaboration has driven the success of OrphanHealthcare. One of his most transformative decisions was the strategic integration of artificial intelligence to support rare disease communities. The launch of the first AI-based chatbot for families affected by rare diseases just right on time for A Vision for the Future of Healthcare Dr. Grossmann envisions a world where healthcare is a shared responsibility rather than a privilege. His goal is to create a global, sustainable ecosystem that fosters collaboration, education, and technological advancement in rare disease treatment. Through corporate partnerships, legislative advocacy, and patient-centric initiatives, he is working to establish a healthcare framework that prioritizes those who have historically been overlooked. Welcoming the new OrphanHealthcare Ambassador, the former Prime Minister of Malta, Josef Muscat. Cuba, the comic hero of the interna?onal book at the office Looking to the future, the opening and further expansion of the OrphanHealthcare Campus in Europe is a key priority. This center of excellence will not only focus on medical and research advances, but will also provide holistic support for patients and their families. By bridging the gap between industry leaders, healthcare professionals, and policymakers, Dr. Grossmann aims to reshape the way rare diseases are diagnosed, treated, and understood on a global scale. donations, leading him to engage corporations, foundations, and entrepreneurs in the fight for rare disease awareness. By demonstrating how social impact and business success can coexist, he has cultivated a network of like-minded individuals who are committed to making a tangible difference in healthcare. LinkedIn, Dr. Grossmann actively builds bridges between different industries to drive innovation in rare disease treatment. Embracing a “Fail, Learn, Go” Mentality: By viewing failures as opportunities for growth, he ensures that new ideas are constantly being tested and refined. Leveraging Technology & Data: Through initiatives like the AI chatbot and digital health platforms with partners, OrphanHealthcare is harnessing the power of “ www.ciobusinessworld.com • • Fostering a Culture of Innovation Innovating with Purpose “ Dr. Grossmann believes that innovation flourishes in an environment that encourages bold thinking and collaboration. His leadership style fosters a culture of resilience and adaptability, focusing on five key pillars: The vision that drives OrphanHealthcare stems from deeply personal experiences and observations. Dr. Grossmann has witnessed the emotional and financial toll that rare diseases take on families. From long diagnostic delays to limited treatment options, the systemic failures in healthcare became evident to him early in his career. His response was to design holistic, patient-centric programs that advocate for faster drug development, patient representation, and legislative changes to improve rare disease care. He also recognized the unsustainability of relying solely on Never leave the vision behind, even when you grow slow or fast, you better think about the next step before. Empowering People with Purpose: Every member of his team understands that their work extends beyond the organization—it is about making a real impact in people’s lives. Encouraging Cross-Sector Collaboration: With a professional network of over 6,400 individuals on • • www.ciobusinessworld.com 14 | March 15 | March

Dr. Grossmann mee?ng with a partner A New Chapter for OrphanHealthcare • • technology to improve patient outcomes. Creating a Safe Space for Creative Thinking: Dr. Grossmann encourages open dialogue and idea- sharing, allowing his team to challenge conventional norms and push boundaries in healthcare innovation. As OrphanHealthcare continues to expand its global footprint, an exciting new development is the appointment of Joseph Muscat, former Prime Minister of Malta, as the organization’s ambassador. This partnership represents a major step forward in advocating for rare disease awareness and healthcare sustainability on an international level. A Career Built on Diversity and Impact Dr. Grossmann’s success is rooted in his diverse career path, spanning medicine, entrepreneurship, public speaking, and consultancy. His ability to adapt to different roles and industries has been instrumental in shaping OrphanHealthcare’s multidisciplinary approach. He believes that true success is not about following a linear path but about continuously learning, evolving, and staying committed to a larger purpose. Dr. Grossmann’s journey from patient to pioneer is a testament to the power of resilience, innovation, and purpose-driven leadership. His work continues to transform lives, challenging the healthcare industry to rethink its approach to rare diseases and patient advocacy. As OrphanHealthcare moves into its next chapter, one thing remains certain—Dr. Frank Grossmann’s vision will continue to inspire and shape the future of global healthcare. Advice for Future Leaders For aspiring leaders and changemakers, Dr. Grossmann emphasizes the importance of resilience, adaptability, and staying true to one’s vision. The journey of creating impact is often slow and challenging, but staying committed to the mission is what ultimately drives meaningful change. He advises the next generation to embrace opportunities outside of traditional career paths, think beyond conventional structures, and remain steadfast in their pursuit of innovation. Website: www.orphanhealthcare.net www.ciobusinessworld.com 16 | March

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I n a rapidly evolving world, visionary personalities are becoming key drivers of change and progress. These individuals are not only influencing industries but also reshaping societal norms and redefining the future. Through innovative thinking, strategic foresight, and a commitment to meaningful impact, these emerging leaders are making a significant difference across technology, healthcare, sustainability, social justice, and business. Their ability to anticipate challenges and create solutions is positioning them at the forefront of global transformation. Unlike conventional leaders who respond to trends, visionary personalities proactively shape the future by introducing new ideas and challenging established norms. Unlike leaders focused solely on financial success, visionary personalities are driven by a broader purpose. Whether addressing social inequality, environmental issues, or technological gaps, they align their goals with creating positive societal and economic change. Their work often reflects a balance between profitability and ethical responsibility. Transformative Impact Across Key Sectors Visionary personalities are influencing a wide range of industries, introducing new ideas and setting new benchmarks for success. Their work is transforming industries and shaping the global economy in profound ways. Defining Traits of Visionary Personalities 1. Technology and Innovation In the technology sector, visionary personalities are driving rapid advancements in artificial intelligence (AI), blockchain, and automation. Their work is transforming how businesses operate and how individuals interact with technology. While visionary personalities emerge from different industries and fields, they share a distinct set of characteristics that drive their success and influence. Their ability to combine creativity with strategic execution sets them apart from traditional leaders. Forward-Thinking and Strategic Insight Visionaries possess a remarkable ability to foresee future trends and disruptions. They analyze complex patterns, understand market dynamics, and anticipate changes before they become mainstream. This allows them to develop innovative strategies and position themselves as industry leaders. Adaptability and Resilience Innovation often involves setbacks and unexpected challenges. Visionary personalities demonstrate resilience by using these setbacks as opportunities to learn and improve. Their ability to adapt and adjust strategies in response to changing circumstances ensures that they remain relevant and effective. Creative and Innovative Thinking Thinking outside the box is a hallmark of visionary leaders. They excel at connecting seemingly unrelated ideas and applying insights from diverse fields to solve complex problems. Their willingness to challenge conventional thinking often leads to groundbreaking solutions. Emotional Intelligence and Influence Visionaries understand the importance of human connection and emotional intelligence. They have the ability to inspire and motivate others, creating a shared sense of purpose and vision. By fostering collaboration and encouraging diverse perspectives, they build strong, effective teams. Commitment to Purpose and Positive Impact 1. Artificial Intelligence and Automation: Visionaries in AI are developing machine learning models that improve decision-making, automate processes, and enhance user experiences. These innovations are increasing efficiency and enabling predictive analysis across industries such as healthcare, finance, and manufacturing. Blockchain and Cybersecurity: Leaders in blockchain technology are creating decentralized systems that enhance data security and transparency. This is reducing the risk of fraud and improving trust in financial and business transactions. Sustainable Technology: Innovators in green technology are developing solutions to reduce carbon emissions and improve energy efficiency. The rise of renewable energy platforms and smart grid technology reflects a growing focus on sustainability. • 2. • • 3. Emerging Visionary Personalities 2. Healthcare and Biotechnology 4. In healthcare, visionary personalities are driving breakthroughs in medical research, personalized medicine, and healthcare delivery. Their work is expanding access to care and improving patient outcomes. Driving Change Precision Medicine and Genomics: Visionaries in biotechnology are harnessing the power of genetic data to create targeted therapies for complex diseases. This • 5. www.ciobusinessworld.com www.ciobusinessworld.com 26 | March 27 | March

personalized approach is improving treatment effectiveness and reducing side effects. Telemedicine and Digital Health: Innovators are developing platforms that enable remote diagnosis and treatment. This has increased access to healthcare, particularly for rural and underserved communities. AI in Diagnostics: Machine learning models are being used to detect diseases and abnormalities in medical imaging with greater accuracy and speed. This has led to earlier interventions and improved patient outcomes. working to reduce incarceration rates and promote rehabilitation. Their focus is on creating fair sentencing policies and improving policing practices. • 5. Business and Finance • Visionary personalities in business and finance are redefining traditional models of economic development and investment. Their work is focused on increasing access to capital and promoting ethical business practices. 3. Environmental Sustainability Fintech and Financial Inclusion: Innovators are creating digital banking platforms and peer-to-peer lending systems that provide financial services to unbanked populations. Sustainable Investment Strategies: Business leaders are prioritizing impact investing and sustainable finance. Their focus is on aligning profitability with social and environmental responsibility. Entrepreneurship and Start-Up Culture: Visionaries are fostering ecosystems that support small businesses and start-ups. Their work is creating jobs and driving economic growth in local communities. • Visionary leaders in sustainability are focused on combating climate change and protecting natural ecosystems. Their work is creating new models for environmental responsibility and resource management. • Renewable Energy Solutions: Innovators are leading the shift from fossil fuels to renewable sources such as solar, wind, and hydroelectric power. Their work is helping reduce carbon emissions and dependence on non-renewable resources. Circular Economy Models: Visionaries are developing closed-loop production systems that minimize waste and maximize resource efficiency. This includes recycling programs and biodegradable materials. Reforestation and Ecosystem Restoration: Environmental leaders are launching large-scale reforestation and conservation projects to protect biodiversity and combat deforestation. • • • Challenges and Barriers While visionary personalities are driving positive change, they face several challenges in sustaining their momentum and expanding their influence. • Regulatory and Policy Barriers: Innovation often outpaces regulation, creating legal and operational uncertainty. Visionaries must engage with policymakers to establish supportive frameworks. Access to Capital and Resources: Expanding innovative solutions requires significant investment. Visionaries must secure funding and form strategic partnerships to scale their impact. Balancing Profitability and Ethical Goals: Visionaries must develop business models that align financial success with positive societal impact. This balance is critical to long-term sustainability. • 4. Social Justice and Equality • Visionaries in social justice are working to dismantle systemic inequalities and promote equal opportunities. Their efforts are focused on creating more inclusive societies and addressing disparities in wealth, education, and representation. • Gender and Racial Equality: Visionaries are leading initiatives to increase diversity in leadership and close wage gaps. Their work includes policy advocacy and public awareness campaigns. Education and Digital Access: Innovators are creating online learning platforms and expanding access to digital tools for underserved communities. This is helping bridge the education gap and empower marginalized groups. Criminal Justice Reform: Social justice advocates are • • • www.ciobusinessworld.com 28 | March

The Role of Leadership in a Changing World eadership is undergoing a profound transformation in L social movements, and environmental challenges are redefining the expectations placed on leaders. In this dynamic and often unpredictable environment, effective leadership requires more than just strategic thinking and decision-making—it demands adaptability, emotional intelligence, and a deep understanding of complex global issues. Leaders who can navigate this shifting landscape and inspire positive change are becoming the driving force behind successful organizations and resilient societies. response to the rapid changes shaping the modern world. Globalization, technological advancements, Adapting to Complexity and Uncertainty The pace of change in today’s world is unprecedented. Technological innovation, political instability, and environmental shifts are creating an environment of constant disruption. Traditional leadership models, built around hierarchical structures and linear decision-making, are no longer sufficient. Leaders are now expected to operate in a more complex and interconnected global landscape, where solutions to challenges are rarely straightforward. Successful leaders in this environment demonstrate a high degree of adaptability. They are comfortable making decisions with incomplete information, adjusting strategies in real time, and responding to unexpected challenges with creativity and resilience. Adaptability also means embracing ambiguity and viewing change as an opportunity rather than a threat. Leaders who can balance short-term agility with long-term vision are better equipped to guide their organizations through uncertainty. www.ciobusinessworld.com www.ciobusinessworld.com 38 | March 39 | March

contribute positively to the communities they serve. Emotional Intelligence and People-Centered Leadership Fostering Innovation and Future-Readiness While strategic and operational skills remain important, the ability to connect with people has become a defining trait of effective leadership. Emotional intelligence—the capacity to understand and manage one’s own emotions while recognizing and influencing the emotions of others—plays a critical role in building trust and fostering collaboration. Innovation is essential for staying competitive in a rapidly changing world. Leaders who encourage creativity, experimentation, and calculated risk-taking create an environment where new ideas can flourish. Empowering teams to challenge existing norms and explore unconventional solutions is key to driving innovation. Leaders who provide psychological safety—where team members feel comfortable taking risks without fear of criticism or failure—are more likely to uncover breakthrough ideas. Modern leaders are expected to demonstrate empathy, active listening, and cultural sensitivity. In a globalized world, diverse teams bring different perspectives and experiences to the table. Leaders who create an inclusive environment where all voices are heard are more likely to inspire loyalty and drive innovation. Emotional intelligence also allows leaders to manage conflict constructively and maintain morale during periods of stress and uncertainty. Future-ready leadership also involves anticipating trends and preparing organizations for the challenges and opportunities of tomorrow. This includes investing in digital transformation, developing talent pipelines, and building resilience against external shocks. Leaders who remain curious, open to learning, and receptive to new technologies and business models are better equipped to lead in an increasingly volatile environment. Moreover, the rise of remote and hybrid work models has created new challenges for leadership. Maintaining team cohesion, ensuring effective communication, and fostering a sense of belonging are essential in a decentralized work environment. Leaders who leverage digital tools and prioritize transparent communication are better positioned to keep their teams aligned and motivated. Conclusion Purpose-Driven and Ethical Leadership Leadership in a changing world requires a blend of strategic insight, emotional intelligence, adaptability, and ethical responsibility. Leaders who can navigate complexity, inspire trust, and drive innovation are best positioned to succeed in today’s dynamic environment. By fostering inclusive cultures, embracing change, and aligning business goals with social impact, modern leaders are not only shaping successful organizations but also contributing to a more sustainable and equitable global future. In a world marked by social and environmental challenges, stakeholders expect leaders to go beyond profitability and demonstrate a commitment to ethical and socially responsible practices. Purpose-driven leadership has become a powerful tool for attracting talent, building brand loyalty, and creating long-term value. Leaders who integrate environmental, social, and governance (ESG) factors into their decision-making are setting new standards for corporate responsibility. Sustainable business practices, diversity and inclusion initiatives, and ethical supply chain management are no longer optional—they are essential components of effective leadership. Additionally, transparency and accountability have become critical to maintaining stakeholder trust. Leaders who communicate openly about challenges and decisions, admit mistakes, and take corrective action are more likely to build credibility and long-term support. Purpose-driven leadership also extends to community engagement and social impact, as organizations are increasingly expected to www.ciobusinessworld.com 40 | March

The Most Impactful And Visionary Personality To Look For in 2025

The Most Impactful And Visionary Personality To Look For in 2025

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