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AroQ AroH AroR

O. CH 2 C COO. O. OOC. CH 2 C COO. [ PapC ]. ADP. APP. +. NAD. CO 2. NH 2. NH 2. NADH. AA. [ AAT ]. +. NH 3. CH 2 CH COO. [ PapB ]. KA. CH 2. APA. COO. C. NH 2. O COO. ADC. pristinamycin. NH 2. chloramphenicol. [ PapA ]. GLU. COO. GLN. CH 2.

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AroQ AroH AroR

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  1. O CH2 C COO O OOC CH2 C COO [PapC] ADP APP + NAD CO2 NH2 NH2 NADH AA [AAT] + NH3 CH2 CH COO [PapB] KA CH2 APA COO C NH2 OCOO ADC pristinamycin NH2 chloramphenicol [PapA] GLU COO GLN CH2 C CHA OCOO AroQ AroH AroR OH + NH3 O OOC CH2 CH COO AA KA OOC [PAT] CH2 C COO AGN PPA AA OH + KA NAD(P) + NAD(P) OH NAD(P)H NAD(P)H [TyrAc] [TyrAp] [TyrAa] NH3 + CO2 CO2 O CH2 C COO CH2 CH COO TyrB AspC HisH Tat TYR HPP OH OH

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