Investigation of ERK1/2 and JNK Phosphorylation in the Lateral Septum Related to DHF

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This study focuses on the phosphorylation status of ERK1/2 and JNK in the lateral septum, utilizing calseq analysis and examining the molecular interplay involving CamKII and GAPDH. Supplemental Figures 1 and 2 highlight variations in signal transduction pathways and protein levels (P-P38, P-JNK, and P-ERK) in response to dynamic heart function (DHF) conditions. Insights from this research could provide valuable information on the role of these pathways in lateral septum activity, further elucidating their contributions to cardiovascular processes.

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Apr 30, 2026

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Investigation of ERK1/2 and JNK Phosphorylation in the Lateral Septum Related to DHF

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CRT DHF Sep Lat Lat Sep JNK 1.2 * 0.8 0.4 0 Ep En Ep En Ep En Ep En JNK ERK 1/2 Lateral Wall ERK1/2 Septum * 3 2 1 0 DHF CRT DHF CRT Supplemental Fig 1
Lateral Septum Ep En Ep En CamKII GAPDH P-P38 P-ERK P-JNK Calseq 1.2 1.2 0.8 0.8 P-P38 CamKII 0.4 0.4 0 0 Lateral Septum Lateral Septum 1.2 1.2 0.8 0.8 P-JNK P-ERK 0.4 0.4 0 0 Lateral Septum Lateral Septum Supplemental Fig 2

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