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Prognostic Impact of PIK3CA Mutation in Cancer: Survival Analysis

This study analyzes the association of PIK3CA mutation with prognosis in cancer patients. Data shows significant survival rates and progression-free survival across different patient groups based on PIK3CA mutation status.

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Prognostic Impact of PIK3CA Mutation in Cancer: Survival Analysis

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  1. Mutation PIK3CA associée à un faible pronostic 100 Pla + T + D : WT Ptz + T + D : WT Pla + T + D : Mut Ptz + T + D : Mut 80 60 Survie sans progression (%) 83 événements45 événements 40 1 événement 20 63 événements 8,6 12,5 13,8 21,8 0 0 3,3 6,6 10,9 13,2 16,4 19,7 23,0 26,3 29,6 32,9 Mois D’après Tao J et al., abstr. S5-7 actualisé

  2. Les courbes K-M par bras montrent un bénéfice seulement dans le groupe EGFR bas EGFR bas EGFR élevé 100 100 90 90 80 80 70 70 60 60 50 50 A A Pourcentage Pourcentage 40 40 B B 30 30 p < 0,001 p = 0,23 C C 20 20 10 10 0 0 0 1 2 3 4 5 6 0 1 2 3 4 5 6 Années depuis la randomisation Années depuis la randomisation D’après Tao J et al., abstr. S5-7 actualisé

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