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glycine n.
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GLYCINE

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  1. GLYCINE Shaun Okano

  2. CHEMICAL FORMULA • C2H5NO2

  3. WHAT IS A GLYCINE? • Amino acid • Simplest • Smallest • 2nd most common • Neurotransmitter • Proteins

  4. PHYSICAL PROPERTIES • Nonpolar • Molecular weight 75.07 • White crystalline powder • Freely soluble in water

  5. CHEMICAL PROPERTIES • Chemical Properties • Aliphatic • No nutritional importance • Codes- GGU, GGC, GGA, GGG Glycine (H2NCH2COOH) ClCH2COOH NH3 + + HCl

  6. NEUROTRANSMITTER • Spinal reflexes • Released into synapse • Binds to receptor • Membrane permeable to Cl- ions • hyperpolarized

  7. BONDING AND ATTRACTION • Covalent bonds • Strong attraction

  8. FUNCTIONS IN THE BODY • Biosynthesis • Nucleic acids • Bile acids • Porphynins • Production of proteins • Collagen • Phospholipids • Prevent muscle degeneration

  9. History 40 Years ago Discovery within the spinal cord and brainstem 2 Years later Neurotransmitter status

  10. USES • Health of prostate gland • Urologic irrigation during surgery • 1.5% concentration of Glycine in water • Minimize risk of intravascular hemolysisduringTUR

  11. SUMMARY • Smallest and Simplest Amino Acids • Hydrogen atom on amine, carboxyl group • Covalent • Neurotransmitter • Used in urological irrigation

  12. END • Glycine (C2H5NO2) • Reference • http://en.wikipedia.org • http://micro.magnet.fsu.edu/aminoacids/pages/glycine.html • http://www.benbest.com/science/anatmind/anatmd10.html#glycine • http://www.biology.arizona.edu/biochemistry/problem_sets/aa/Glycine.html • http://www.chemie.fu-berlin.de/chemistry/bio/aminoacid/glycin_en.html • http://www.supplementnews.org/glycine/ • http://www.drugs.com/pro/glycine.html • http://www.ncbi.nlm.nih.gov/pubmed/16402094