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Explore the intricacies of DNA, its structure, replication process, and the groundbreaking discoveries of Chargaff, Watson, and Crick. Understand how DNA polymerase, nucleotides, and hydrogen bonds play key roles in DNA replication and maintenance. Delve into the double helix structure that defines life's genetic material.
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Ch. 14 DNA – The Genetic Material By: NasAnesi, Joshua Tuaniga, Anthony Ortiz
DNA Replication • DNA replication requires a template, nucleotides, and a polymerase enzyme • New DNA molecules are produced by DNA polymerase copying a template • In replication, the process produces two new molecules each composed of one new strand and one old strand • When DNA is replicated, the 2 strands are split and each strand is transcripted to produce a new strand
DNA Structure • Nucleotide building blocks for DNA: adenine, guanine, cytosine, and thymine. • In DNA, Erwin Chargaff found out that there were equal amounts of adenine and thymine, and of cytosine and guanine. • Watson and Crick found that DNA had 3 main components; 1. a five carbon sugar, 2. a phosphate group, 3. and an nitrogenous base • DNA’s backbone has a phosphodiester backbone and is also a double helix • Double helix is made up of long polymers of nucleotides • Watson and Crick also proposed that the two strands were held together by formation of hydrogen bonds between bases on opposite strands
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