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Gamma-1: Five Year Follow-up Vascular Gamma Brachytherapy vs placebo for In-stent Restenosis in Native Coronary Lesions. MACE: Death, MI or TLR at 5 years. p = 0.380. p = 0.254. p = 0.064. %. p = 1.000. Gamma-1: Five Year Follow-up.

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## Gamma-1: Five Year Follow-up Vascular Gamma Brachytherapy vs placebo for In-stent Restenosis in Native Coronary Lesions

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**Gamma-1: Five Year Follow-upVascular Gamma Brachytherapy vs**placebo for In-stent Restenosis in Native Coronary Lesions MACE: Death, MI or TLR at 5 years p = 0.380 p = 0.254 p = 0.064 % p = 1.000**Gamma-1: Five Year Follow-up**• Among patients treated with gamma brachytherapy or placebo for in-stent restenosis in native coronary lesions, there were no statistically significant differences in MACE, TLR, or TVR at five-years. • The risk of recurrent MI tended to be higher among patients treated with gamma brachytherapy (p=0.06) • While there was a clinical benefit at 9 months for gamma brachytherapy, these five-year results demonstrate no significant benefit of gamma brahcytherapy consistent with a “late catch-up” or delay in restenosis among these patients.

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