Journal Club. Jim Hoehns, Pharm.D. Edoxaban. Oral factor Xa inhibitor Bioavailability: 62% Tmax : 1-2 hrs Elimination: 50% renal Half-life: 9-11 hours. ENGAGE AF-TIMI 48. Randomized, double-blind, double-dummy trial N=21,105 patients with Afib Median follow-up: 2.8 years
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Jim Hoehns, Pharm.D.
* Significantly different (P<0.05)