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Blood Pressure Regulation- Background info. Water will go where there are high concentrations of Salt Increase in water = increase in volume Increase in volume = increase in pressure. Blood Pressure regulation. 1) If Low Blood Pressure (BP) Juxtaglomerular Apparatus secretes renin.

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blood pressure regulation background info
Blood Pressure Regulation- Background info
  • Water will go where there are high concentrations of Salt
  • Increase in water = increase in volume
  • Increase in volume = increase in pressure
blood pressure regulation
Blood Pressure regulation
  • 1) If Low Blood Pressure (BP)
        • Juxtaglomerular Apparatus secretes renin
blood pressure regulation1
Blood Pressure regulation
  • 1) If Low Blood Pressure (BP)

Aldosterone

        • Renin is an enzyme that changes angiotensinogen into Angiotensin I
        • Angiotensin I is then converted into Angiotensin II
        • Angiotensin II stimulates the adrenal cortex to release aldosterone
blood pressure regulation2
Blood Pressure regulation
  • 1) If Low Blood Pressure (BP)
        • Aldosterone promotes the excretion of K+ and the reabsorption of Na+
        • The reabsorption of Na+ is followed by the reabsorption of H2O
        • Blood volume and blood pressure increase
16 3 regulatory functions of the kidneys
16.3 Regulatory Functions of the Kidneys
  • 2) If High Blood Pressure (BP)

Atrial naturietic hormone (ANH)

        • Another hormone regulating sodium
        • Secreted by right atrium of heart in response to stretching
        • Indicates increased blood volume
        • Inhibits renin secretion by juxtaglomerular apparatus
        • Inhibits aldosterone release
        • Promotes sodium excretion - natriuresis
16 3 regulatory functions of the kidneys1
16.3 Regulatory Functions of the Kidneys

-3) Permeability of collecting duct is under hormonal control

  • Antidiuretic hormone (ADH)
    • `is released by the posterior pituitary gland (made by the hypothalamus) to regulate BP
    • In the presence of ADH, the collecting duct become more permeable to water
    • Water will leave the kidney and enter blood (↑BP) and a concentrated urine is produced
    • In the absence of ADH, the collecting duct become less permeable to water
    • Water will not leave the kidney and a dilute urine is produced
16 3 regulatory functions of the kidneys2
16.3 Regulatory Functions of the Kidneys
  • Diuretics
    • Increase flow of urine
    • Alcohol
      • Shuts off ADH (antidiuretic hormone) causing larger urine volumes
      • Dehydration causes hangover
    • Caffeine
      • Increases glomerular filtration rate
      • Decreases tubular reabsorption of sodium
    • Diuretic drugs
      • Many inhibit active transport of sodium at loop of the nephron
summary
Summary
  • Know the background info
  • Know the mechanisms of the 3 hormones that regulate blood pressure