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Etude de l axe de la croissance staturale

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Etude de l axe de la croissance staturale

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    1. Etude de l’axe de la croissance staturale 1- Les facteurs Hypothalamiques (GHRH, Ghréline, SS-14) 2- Le facteur Antéhypophysaire : la GH 3- Le facteur Hépatique : l’IGF1 4- Régulation de l’axe de la croissance staturale (Régulation de la libération de la GH) 5- Mécanisme moléculaire d’action de la GH 6- GH endocrine / paracrine / autocrine 7- Autres fonctions de la Somatostatine 14 (SS-14)

    2. Axe de la croissance staturale (10) Liaison GH – GHR 1 molécule GH 2 sites de liaison avec 2 molécules GH-R Dimérisation Activation de GH-R

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