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Big data and the promise of personalized medicine

Big data and the promise of personalized medicine. Indrek Vainu Helsinki Business Hub indrek.vainu@helsinkibusinesshub.fi Mobile: +358 44 746 3902. Hello!. What is Personalized Medicine?. Customization of healthcare – decisions, practices, products tailored to individual patients.

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Big data and the promise of personalized medicine

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  1. Big data and the promise of personalized medicine Indrek Vainu Helsinki Business Hub indrek.vainu@helsinkibusinesshub.fi Mobile: +358 44 746 3902

  2. Hello!

  3. What is Personalized Medicine? Customization of healthcare – decisions, practices, products tailored to individual patients

  4. A lot of data • The source code of you => 3.2 billion base pairs • Sequenced => 700 MB of data http://cdn.trendhunterstatic.com/thumbs/illumina-hiseq-2500.jpeg http://thewinnower.com/blog/rejected-pt-1/

  5. Beating Moore’s law http://www.genome.gov/images/content/cost_per_genome_apr.jpg

  6. Biobanks + data centers http://www.ebo-enterprises.com/sites/default/files/images/07-14datacenter_lg.jpg

  7. Genomics ROI “Every dollar we invested to map the human genome returned $140 to our economy.” --President Barack Obama, 2013 State of the Union address, Feb. 12, 2013 http://web.ornl.gov/sci/techresources/Human_Genome/publicat/BattelleReport2011.pdf

  8. In the news …

  9. The promise? http://www.condenaststore.com/-sp/Here-s-to-the-human-genome-and-its-potential-in-finding-at-long-last-a-Cartoon-Prints_i8643225_.htm

  10. The basis for personalized medicine

  11. Benefits • Genetic testing to select drugs • Xalkori, non-small cell lung cancer drug • Treatment cost $10,000 / month • Works only for ALK-positive gene mutation patients (3-5%) • Testing costs $400 • 24 out of 25 patients do not respond • BOTTOM LINE => testing all $10,000 vs $250,000/month • Categorized treatment plans • Identifying responding patients http://abcnews.go.com/Health/CancerPreventionAndTreatment/lung-cancer-pill-crizotinib-highlights-improved-iding-treating/story?id=14414833

  12. Finland well positioned • Finland has: • several biobanks • unique genomic composition • electronic medical records • research infrastructure • Recently: • Biobank Act to use biobank data for research purposes

  13. Thank you 

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