1 / 11

Lecture 3: Single gene inheritance

Lecture 3: Single gene inheritance. Mutations. Haploinsufficient phenotpyes. Pax 6 mutation. normal. AC absent. Olfactory bulb hypoplasia. Pax 6 mutation phenotype: aniridia , hyposmia. Single gene inheritance in haploids: budding yeast. ascus. Products of meiosis in yeast.

radwan
Download Presentation

Lecture 3: Single gene inheritance

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Lecture 3:Single gene inheritance

  2. Mutations

  3. Haploinsufficientphenotpyes Pax 6 mutation normal AC absent Olfactory bulb hypoplasia Pax 6 mutation phenotype: aniridia, hyposmia

  4. Single gene inheritance in haploids:budding yeast ascus

  5. Products of meiosis in yeast

  6. X-linked inheritance

  7. Human X and Y chromosomes Y-chromosome genes?

  8. Pedigree symbols

  9. Autosomal recessive pedigree Mendelian rules apply, but Mendelian ratios are not observed b/c of small sample size Examples: cystic fibrosis, sickle-cell anemia, albinism, Tay-Sachs disease, PKU

  10. Homozygous recessives from inbreeding

More Related