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  1. WELCOME TO BIO 171 INTEGRATED BIOLOGY a course for majors “Non-majors bio is a buffet with a little taste of each topic, a majors course is like a full course meal” -former Bio 171 student

  2. Dr. Charissa Urbano B.S. Bowling Green State University Physical education, coaching, biology M.A.E. Ball State University Science Education, bioethics Ed.D. Ball State University mol; molecular biology w/ research in teratology

  3. WHO ARE YOU?

  4. Why Are You Here?

  5. Words of Wisdom • Secrets of Success http://www.delta.edu/cmurbano • Labs are your friend: Don’t miss any!! • Budget your time – exams in ATC. • Check EDUCATOR often for class updates. • How do I get an “A” earn it by spending time, time, time outside of class learning to master key concepts fundamental to all bio.

  6. PEER MENTOR • someone like you - similar goals • successfully completed BIO 171 • experience under their belt • serve as a model student • It’s all about teamwork

  7. HOW CAN A PEER MENTOR HELP? • Study skills • Test preparation • Time management • Lab reports & data analysis • Research projects • Laboratory procedures

  8. Are You Ready for This? My assumptions are: • Want to be here ... motivated, self-directed learner who’s going somewhere. • Have a solid background in biology & chemistry • Like to be challenged • Pre-Assessment test doesn’t freak you out

  9. INTEGRATED BIOLOGY Integrated means we’ll be studying all forms of life 6 KINGDOMS focus will be on similarities and differences

  10. Figure 1.11 Three domains, six kingdoms Eukarya

  11. Who Else Uses an Integrated Approach • University of Michigan • MSU • Ferris State • Wayne State • Most other 4 year schools except.....

  12. The Good ‘Ol Classical Approach 1 semester - Zoology 1 semester - Botany svsu, cmu

  13. COURSE CONTENT BIO 171 Biochemistry Cells Metabolism Genetics Development

  14. BIO 171 the SYLLABUS is your CONTRACT FOR SUCCESS ask questions via DB

  15. The Major Themes & Schemes in the study of biology

  16. Figure 1.14 Charles Darwin (1809–1882) Biology’s Core Theme • Applies to ALL life • Connects all areas of biology from the micro to the macro level • Explains the relationship between the physical environment and the living world. • Genome information has corroborated all aspects of this key idea and left room for little the opposition • Look for evidence in every chapter • See Darwin’s Idea lecture and Stephen Jay Gould This View of Life

  17. Concept 1.1 Biologists explore life from the microscopic to the global scale

  18. Figure 2.1 The hierarchy of biological order from atom to organism

  19. Figure 1.2 The hierarchy of biological organization

  20. Concept 1.2 Biological systems are much more than the sum of their parts

  21. Emergent Properties of Systems macromolecules cells systems species community biosphere The sum is greater than the parts

  22. Properties of Life growth & development order regulation metabolism adaptation response

  23. The Power and Limitations of Reductionism

  24. Systems Biology • Interdisciplinary research teams • Bioinformatics • Pathways

  25. Feedback Regulation Negative Feedback & Positive Feedback It’s a concentration thing Homeostasis

  26. Concept 1.3 Biologists explore the diversity of life

  27. Grouping & Classifying Interrelationships within the tree of life

  28. Figure 1.11 Three domains of life Eukarya

  29. Basic Unit of Life

  30. Domains & Cell Types Prokaryotic – before a Eubacteria Archea Eukaryotic - inner membranes

  31. Continuity of Life Continuous passage of DNA from generation to generation throughout the history of life This genetic history is the biological “holy grail” it tells the story, mutation by mutation of the history of life on earth

  32. Figure 1.5 The genetic material: DNA Allows us to trace molecular evolution Genographic Project

  33. Structure Fits Function • Formfits function at all levels – even the engineers know this ;-) • molecules, cells, organs, & organisms are built for efficiency

  34. Figure 1.6 Form fits function

  35. Unity In Diversity DIVERSITY • diversity is a hallmark of life • 1.5 million species have been named • 6 distinct kingdoms UNITY • 6 elements • 4 macromolecules • 1 genetic code • Basic unit of all life - cell

  36. Figure 1.9 A small sample of biological diversity

  37. Figure 1.12 An example of unity underlying the diversity of life: the architecture of eukaryotic cilia

  38. Concept 1.4 Evolution accounts for life’s unity and diversity

  39. Figure 1.14 Charles Darwin (1809–1882)

  40. The Core Theme: Evolution “Nothing in biology makes sense except in light of evolution” Theodosius Dobzhansky