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Shaping the Future of Sight

Shaping the Future of Sight. Proven ZEISS Optic for aspheric preloaded IOLs. CT ASPHINA ® 613P (1).

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Shaping the Future of Sight

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  1. Shaping the Future of Sight Proven ZEISS Optic for aspheric preloaded IOLs CT ASPHINA® 613P (1) • CT ASPHINA® 613P is the same IOL model as CT ASPHINA® 603P (formerly known as XL Stabi ZO). The only difference is the new design of the preloaded cassette that is used exclusively with SkyJet ® Advanced. • CT ASPHINA® 604P is the same IOL model as the formerly known Invent ZO. CT ASPHINA® 604P (2)

  2. “Zeissgeist” in optical design

  3. Advancing aspherics Carl Zeiss has a long history of experience in developing aspheric lens concepts and solutions for a variety of products and systems. In fact, with many of its innovative developments, ZEISS has managed to literally capture the zeitgeist(1) of a technological era. Consider such milestones as the first aspheres to correct astigmatisms (1899) or a novel retrofocus type aspheric lens for high-speed motion picture cameras (1975), to name but two. Consider such ZEISS milestones as: “Zeissgeist” in optical design Microscope with aspheric optic design Aspheric optic for binoculars Photo camera objective with aspheric lens (1) Spirit of the times

  4. New generation of aspheric IOLs For more than a century now, Carl Zeiss has defined high-level quality, unparalleled optical expertise and outstanding innovation in optical technology. For the first time, ZEISS has applied this proven technology to a new generation of aspheric IOLs used in cataract surgery. Introducing the first members of the ZEISS Optic aspheric IOL family: the CT ASPHINA 613P and the CT ASPHINA 604P. “Zeissgeist” in optical design

  5. ZEISS in your eyes Precision of the concept

  6. Precision of the ZO (600) asphericity concept In developing its aspheric lens concept, ZEISS combined the best of both worlds: the advantages of negative spherical aberrations IOLs and aberration-neutral IOLs. The unique ZO / 600 asphericity concept is designed to: correct a part of the spherical aberrations of the pseudophakic eye be less sensitive to decentration and tilt improve the retinal image quality of patients vs. spherical IOL maintain depth of field vs. spherical IOL offer maximum visual performance for the largest range of patients be used in routine and be adapted for the vast majority of patients ZEISS in your eyes –Precision of the designed asphericity concept

  7. The benchmark among eye models The advanced ZEISS aspheric lens is patterned after the Liou & Brennan (LBE) eye model, widely regarded as the most anatomically accurate eye model in ophthalmology today. LBE places the young, phakic human eye into an optical, physiological and realistic environment, using, among other things, the physiological off-axis of the pupil in nasal and the tilt of the visual/optical axis as its basis. Similarly, the ZEISS Optic / 600 concept closely mimics the anatomical and optical imaging properties of the young, natural human eye. ZEISS in your eyes – A recognized eye model The ZO / 600 lens design is based on the widely recognized Liou and Brennan (LBE) eye model

  8. Proven optical excellence CT ASPHINA® 613P CT ASPHINA® 604P Performance of the concept

  9. A full range of clinically proven advantages for surgeons and patients The unique and well-known ZEISS aspheric Optic / 600 concept combines the advantages of negative spherical aberration IOLs and aberration neutral IOLs correcting a part of spherical aberrations, maintaining depth of field, and optimizing visual performance for the largest range of patients. The ZO (600) IOLs offer a full range of clinically proven advantages for surgeons and patients. Confidence in a well-known ZEISS aspheric optic Proven efficacy of the asphericity optic concept (A) Proven to provide the same amount of SA as the natural young crystalline lens (B) Proven better visual performance vs. spherical IOL (B) Proven to maintain depth of field vs. spherical IOL(B) Proven precise, reproducible and stable outcomes (A&B) For routine use and adaptation to the vast majority of patients (A&B) Proven optical excellence of the ZO (600) IOLs

  10. Proven optical excellence of the ZO (600) IOLs Maximum visual performance for the largest range of patients The optic of the ZO (600) IOLs closely mimics the anatomical and optical properties of young phakic eyes for the largest range of spatial frequencies. Eyes implanted with ZEISS Optic / 600 asphericity concept IOLs show a similar amount of spherical aberrations to the phakic eyes from the control group (Graph 1) (A). Graph 1: MTF curve of the ZO (600) IOL group is similar to the MTF curve of the young phakic eyes control group, showing that the IOL mimics the SA of the natural crystalline lens in a stable way (12 month post-op.). (OPD-Scan measurement)

  11. Proven optical excellence of the ZO (600) IOLs Maintained depth of field The development of the optical concept of the ZO (600) IOLs is based on the Liou & Brennan eye model, the most anatomically accurate eye model, allowing the IOLs to have low sensitivity to tilt & decentration (B). The concept also keeps a small amount of spherical aberrations, maintaining depth of field in implanted eyes equivalent to spherical IOL implanted eyes (Graph 2) (B). Graph 2: Depth of field of eyes implanted with ZO (600) IOLs is comparable to the depth of field of eyes implanted with spherical IOLs. At 1 year follow-up.

  12. Proven optical excellence of the ZO (600) IOLs Depth of field – Simulated image The 2 pictures below clearly show the impact of the depth of field on the quality of the image, it’s really an advantage for patients that ZO (600) IOLs maintain depth of field. Vision with an excellent depth of field Vision with a reduced depth of field

  13. Proven optical excellence of the ZO (600) IOLs Superior optical performance compared to a spherical IOL Due to their innovative aspheric concept, ZO (600) IOLs outperform spherical IOLs by improving the quality of the image (Graph 3) (B). Graph 3: MTF curve of aspheric ZEISS Optic (600) IOLs is superior to MTF curve of spherical IOLs, showing a higher quality of vision for the patients implanted with the aspheric IOLs. Statistically significant difference at all spatial frequencies evaluated. (Wasca Analyzer measurement)

  14. Proven optical excellence of the ZO (600) IOLs Visual performance - Compared images of ZO (600) IOL vs. spherical IOL Vision with the aspheric optic of the CT ASPHINA 613P Vision through a spherical optic

  15. CT ASPHINA® 613P & CT ASPHINA® 604PIOLs overview CT ASPHINA® 613P CT ASPHINA® 604P Technical Features

  16. Safe, established hydrophilic acrylic material used for over 15 years (C,D,E,F,G) The hydrophilic acrylic of the ZO (600) IOLs has successfully demonstrated its excellent long term behavior on the market in terms of: biocompatibility (C) transparency (C) stability (C) good resistance to injection stress and Nd:YAG laser (C) very low incidence of glare, blurring and halos (B) Less bacterial adhesion of hydrophilic acrylic material (D) Low silicone oil adherence (C) CT ASPHINA 613P & CT ASPHINA 604PIOLs overview -Benefit from a trustworthy IOL platform

  17. Stable design and reliable behavior The CT ASPHINA 613P and CT ASPHINA 604P feature a 3- and 4-haptics design respectively to: optimize the contact surface with the equator of the capsular bag and to secure postoperative stability The well-known 3-haptic design of the CT ASPHINA613P is highly recognized: confidence in the 3-haptic design IOL platform with several hundred thousand IOLs implanted worldwide (C) low occurrence of tilt and decentration observed (B) CT ASPHINA 613P & CT ASPHINA 604P IOLs overview -Benefit from a trustworthy IOL platform

  18. Well-known ergonomy and safety The CT ASPHINA 613P and CT ASPHINA 604P IOLs are preloaded in their respective cartridge to allow for an easy, sterile and reproducible application. The IOLs are protected at all times and never handled to avoid risk of damage, misloading and cross-contamination. Simply clip the cassette into the disposable injector, add the viscoelastic and it’s ready for implantation. CT ASPHINA 613P & CT ASPHINA 604P IOL overview –Quick 3-step preparation Only 3 steps to be ready for implantation Step 1 Ready for implantation Step 2 Step 3 • confidence in a well-established, for over 7 years, disposable injector system • safety of the preloaded IOLs • ease of use from preparation to implantation

  19. CT ASPHINA 604P Posterior ZEISS aspheric optic Preloaded IOL Hydrophilic acrylic (28%) Optical ø: 6.0 mm Total ø: 10.5 mm Angulation: 0° A-Constant (estimated): 118.1 Biconvex ACD: 5.02 Diopters: +14 to +30 D by 0.5 D increments Square edge UV filter Injectable with the SkyInvent disposable injector CT ASPHINA 604P –Technical features

  20. CT ASPHINA 613P Posterior ZEISS aspheric optic Preloaded IOL Hydrophilic acrylic (28%) Optical ø: 6.0 mm Total ø: 10.5 mm Angulation: 10° A-Constant (estimated): 118.2 Biconvex ACD: 5.08 Diopters: +10 to +25 D* by 0.5 D increments Square edge UV filter Injectable with the new SkyJet Advanced* disposable injector CT ASPHINA 613P –Technical features (*) For diopters from +25.5 to +30 D please continue to use CT ASPHINA 603P with the regular SkyJet

  21. “I am a long time user of the ZEISS aspheric 3-haptic preloaded IOLs with the SkyJet injector system as they offer precise, stable and efficient outcomes for routine cataract surgery. I was waiting for a new, smaller incision injector and now it’s done with SkyJet Advanced so the combination is even more attractive” Dr. Gilles DENIS, MD, France Much smaller incision SkyJet Advanced allows for an ergonomic, reliable and predictable implantation of the CT ASPHINA 613P through a much smaller incision. The diameter of the SkyJet Advanced injection tip is significantly reduced compared to the regular SkyJet, making the incision size required to inject the IOL much smaller. SkyJet Advanced- the new, smaller incision injector only for CT ASPHINA 613P Reduced surface of the SkyJet Advanced tip

  22. SkyJet Advanced- the new, smaller incision injector only for CT ASPHINA613P • Predictable, controlled and safe IOL delivery • The SkyJet Advanced further improves reproducibility of injection due to a new plunger and a new design of the preloaded cassette. The precise folding of the IOL, its centered, straight and controlled delivery into the capsular bag, makes the injection very safe, predictable and comfortable. • Take advantage of the new and impressive SkyJet Advanced to maximize efficiency, safety and reproducibility by implanting the proven CT ASPHINA 613P through a much smaller incision for improved outcomes, optimized surgical workflow and happier patients.

  23. SkyJet Advanced, the new smaller incision injector only for CT ASPHINA 613P • Minimal incision, maximum performance • Due to a thinner injection tip, a new design of preloaded cassette and a new plunger, this unique premium combination of a proven innovative aspheric optic preloaded IOL and a high-tech injector allows for an ergonomic, reliable and reproducible implantation of CT ASPHINA 613P, through a significantly reduced incision size.

  24. An eye for patient well-being Patient Care

  25. Patient Care Cataract surgery has become a very routine procedure. But when it comes to patient safety and well-being, there is no room for compromise. The advanced lens concept of the ZEISS Optic (600) is designed to ensure a highly reproducible and precise refractive outcomes, enabling routine adaptation to the vast majority of patients. Moreover, it delivers the best image quality the retina can process while preserving the depth of field. An eye for patient well-being

  26. Great mileage The ZEISS aspheric lens displays very high stability, allowing patients to benefit from: secure long-term lens centration optimized optical performance over a longer period of time An eye for patient well-being

  27. References Note: IOLs and injectors are not available in all countries. Please ask our local representatives for the status of the products in your country.

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