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David van Bodegom MD PhD Leiden University Medical Centre Dept. Gerontology & Geriatrics

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Health & life research project. David van Bodegom MD PhD Leiden University Medical Centre Dept. Gerontology & Geriatrics. Map by Dr. Linda May. Health & Life research project. ~30.000 participants 10 year demographic follow up for birth and survival

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Presentation Transcript
slide1
Health & life research project

David van Bodegom MD PhD

Leiden University Medical Centre

Dept. Gerontology & Geriatrics

health life research project
Health & Life research project

~30.000 participants

10 year demographic follow up for birth and survival

Environmental information (all 1700 households)

-Drinking source

-Socio-economic data

Genetic information (kin information, >10.000 participants, custom SNP-chip)

Clinical information

Cardiovascular studies, biometric studies, immulogical assays, blood and stool samples

Cause of death (verbal autopsies, n=1277)

slide4
Age-distribution

Meij et al., Trans Trop Hyg (2009)

slide9
Compound

River

Hydrology data CERGIS

Legon University,

Accra, Ghana

2 km

slide10
Compound

River

Well

Hydrology data CERGIS

Legon University,

Accra, Ghana

2 km

slide11
Compound

River

Well

Borehole

Hydrology data CERGIS

Legon University,

Accra, Ghana

2 km

slide12
Compound

River

Well

Borehole

Hydrology data CERGIS

Legon University,

Accra, Ghana

2 km

kin information
Kin information

Family structures

Van Bodegom et al, Gerontology 2010

Van Bodegom et al, Biodemography 2012 in press

slide16
IL 10 Gene & inflammatory capacity

IL-10 SNPS

Van Bodegom, Ann. NY acad. Sc (2008)

Kuningas et al, Plos One (2009)

inflammation old age survival
Inflammation & (old age) survival

Kuningas et al, Plos One (2009)

figuur bart
Figuur bart.

Koopman et al., Plos One 2012

Koopman et al., Lancet 2012, in press

slide19
Department of Gerontology & Geriatrics

Prof Rudi Westendorp MD PhD

Hans Meij PhD

Maris Kuningas PhD

David van Bodegom MD

Maarten Rozing MD

Eric Sanchez-Faddiev

Ulrika Eriksson PhD

Bart Koopman

Anita van de Biggelaar PhD

Students:

Diana, Yasha, Stephan, Karin, Arianne, Vanessa, Gretty, Debby, Tirsa, Maurits, Toke,

Ghana Health Service

People of the Garu Tempane district

Local co-workers: Daniel, Moses, John, John Abugri, Dent, Simon, Thomas, Hawa, Paschalina, Justice, Lizzy, Awel, Alex, Judas

Department of Human Genetics

Prof Peter de Knijff

Jeroen Pijpe

Department of Parasitology

Ton Polderman PhD

Lisette van Lieshout PhD

Prof Maria Yazdanbakhsh MD

Linda May PhD

Institute Biology Leiden

Bas Zwaan PhD

Sociology, VU University A’dam

Fleur Thomese PhD

Ralf Kaptijn

University of Tamale, Ghana

Juventus Ziem MD PhD

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