Magnesium: The First Line of Psychiatric Depression Defence - Pubrica

1. MAGNESIUM: THE FIRST LINE OF PSYCHIATRIC DEPRESSION DEFENCE An Academic presentation by Dr. Nancy Agens, Head, Technical Operations, Pubrica Group:  www.pubrica.com Email: sales@pubrica.com

2. Today's Discussion Outline Introduction The Role of Magnesium in our Body The Ways Magnesium gets Depleted Effects of Magnesium Administration

3. Introduction World Health Report states that depression accounts for 40% of all neuropsychiatric disorders. Depression is a disease characterized by a lack of energy, mood swings, fluctuations in weight, interrupted sleep, waking up very early morning, gain or loss of appetite, etc. Reduction in brain magnesium levels results in lowering of serotonin. Major depression is terminated with oral and intravenous administration of magnesium. Administration of antidepressant drugs raises the level of magnesium concentration.

4. Role of Magnesium in our Body Magnesium plays a crucial role in medical regulating contraction of all kinds of muscles, blood pressure, metabolism of insulin, synthesis of DNA, RNA and proteins. In clinical care, the central nervous system has the maximum concentration of magnesium which accounts for brain balance. Magnesium acts as a voltage-dependent blocker of N-methyl-D-aspartate channel. This channel is responsible for regulating the flow of calcium to the neuron. In such medical conditions, calcium and glutamate are take up by the neuron instead magnesium, which in turn leads to deregulation of synaptic function, finally leading to the condition of depression.

5. Ways Magnesium gets Depleted Processed foods lack magnesium and their intake results in magnesium deficiency in our body. Black beans, pumpkin seeds, cashews, almonds and dark chocolate are some of the food items rich in magnesium. Intake of antacids, diuretics, caffeine and alcohol also decreases magnesium levels. Use of pesticides and potassium-based fertilizers causes magnesium depletion. Pesticides kill the important magnesium absorbing bacteria, while potassium of fertilizers is taken up by the plants instead of magnesium and calcium.

6. Effects of Magnesium Administration The positive side is that mood and cognition gets improved and better with the administration of magnesium such that the normal levels of magnesium gets restored in the body. People tend to show healthy eating patterns, better quality of sleep, improvements in efficacy of modalities such as medications, etc. Minerals like magnesium are required in very small amounts in our body but play major roles in several metabolic pathways.

7. Contact Us UNITED KINGDOM +44-1143520021 INDIA +91-9884350006 EMAIL sales@pubrica.com