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Rashida Ferrand rashida.ferrand@lshtm.ac.uk

Getting to the first 95 for children and adolescents: Innovative approaches for pediatric case finding IAS Satellite Session – JSI/AIDSFree Project and Partners July 23, 2018 8 – 10 am. Rashida Ferrand rashida.ferrand@lshtm.ac.uk. Dynamics of the paediatric HIV epidemic.

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Rashida Ferrand rashida.ferrand@lshtm.ac.uk

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  1. Getting to the first 95 for children and adolescents: Innovative approaches for pediatric case findingIAS Satellite Session – JSI/AIDSFree Project and PartnersJuly 23, 2018 8–10 am Rashida Ferrand rashida.ferrand@lshtm.ac.uk

  2. Dynamics of the paediatric HIV epidemic • Dramatic scale up of Prevention of mother-to-child transmission (PMTCT) programmes across Africa • PMTCT coverage variable across the region • “PMTCT” includes HIV testing of HIV-exposed infants & early infant diagnosis (EID); rates remain poor • A third of infected infants have “slow-progressing” disease―median survival 16 years: identified in older childhood UNAIDS Global Report 2017 Wettstein C et al AIDS 2012 Ferrand RA et al AIDS 2009

  3. Barriers to HIV testing in children Kranzer K et al PloS Med 2014; Bandason T et al AIDS Care 2013;

  4. “The first 95” • 95% of individuals with HIV will be diagnosed by 2030 • Testing strategies have targeted infants (PMTCT) and adults • Strategies will need to take into account: • Barriers to testing in children • Physical and social heterogeneity across childhood • Dropping incidence in children

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