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This study explores the effects of JNK pathway inhibition on TNFα-induced responses in thyroid cancer cells. Results suggest that targeting JNK signaling could be a potential therapeutic strategy for suppressing TNFα-mediated effects in thyroid cancer.
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GFP mIBα JNK1 n.s. ppJNK JNK2 JNK1 BCPAP JNK JNK2 -tubulin JNK1 n.s. ppJNK JNK2 SW1736 JNK1 JNK JNK2 -tubulin JNK1 n.s. ppJNK JNK2 JNK1 TPC1 JNK JNK2 -tubulin JNK1 n.s. ppJNK JNK2 JNK1 JNK C643 JNK2 -tubulin TNFα (h) 0 0.5 1 2 4 8 16 0 0.5 1 2 4 8 16