IMPACT OF PREECLAMPSIA ON BIRTH OUTCOMES Xu Xiong, MD, DrPH Department of Obstetrics and Gynecology Université de Montréal, Quebec, Canada Preeclampsia A syndrome characterized mainly by hypertension and proteinuria after 20 weeks of gestation.
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Xu Xiong, MD, DrPHDepartment of Obstetrics and GynecologyUniversité de Montréal, Quebec, Canada
Fig 4. Preeclampsia & High Birth Weight (>4000 g)(N=14,461, Suzhou, China, 1989-1990)
Fig 5. PIH and High Birth Weight (>4200 g)(N=97,270 Alberta, Canada)
Fig 6. PIH and Large for Gestational Age (N=97,270 Alberta, Canada)
Preeclampsia and fetal growth(Xiong et al, Am J Obstet Gynecol 1999;180:207-13)(Xiong et al, Am J Obstet Gynecol 2000;183:148-55)
Data from Canada, China, Europe, South-Africa, US (CPEP trial) show that preeclampsia is also associated with an increased rate of high birth weight.
Fig. 7 Effect of PIH on birth weight by gestational age(Xiong et al, American Journal of Epidemiology, 2002;155:203-9)
Most babies born to mothers with preeclampsia, especially born at term, have normal fetal growth. These findings do not endorse the currently held theory that reduced uteroplacental perfusion is the unique pathophysiologic process in preeclampsia.